DRSC/TRiP Functional Genomics Resources

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Protein Alignment mthl4 and Adgrf2

DIOPT Version :9

Sequence 1:NP_788394.1 Gene:mthl4 / 36960 FlyBaseID:FBgn0034219 Length:517 Species:Drosophila melanogaster
Sequence 2:XP_017452241.2 Gene:Adgrf2 / 301269 RGDID:1306718 Length:654 Species:Rattus norvegicus


Alignment Length:442 Identity:96/442 - (21%)
Similarity:163/442 - (36%) Gaps:121/442 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly    46 GLLIPAH-LTAEYDYKLLADDSKEKVASHVRGCACHLRPCIRFCCPQYQKMQKSKCYGDMSEDEL 109
            |.::|.: |...:.:.:..:|:.:||...:.                            ::.:||
  Rat   233 GTVVPRNSLGKNFTFSMRVNDTSDKVTGRIL----------------------------LTTEEL 269

  Fly   110 NKHDPFVNV------TLSDGSVVRRHFKEDLIVQSDLAKPGCPRMYFLNHELPGNEFTLFEN--- 165
            .|......|      ||  |:::.....|::.|.      |......|..||. |...:||.   
  Rat   270 QKVPSAFQVISIAFPTL--GAILEASLLENMTVN------GLVLSVILPKELK-NISLIFEKIRK 325

  Fly   166 -----------GSLLRHWDK-----VELSKRE---YCVQHLSFKDDSIRIAPHF--CPLSSEHSR 209
                       .||...||:     ::.:.|:   .|..:..|...||.::|:.  .|:.:..:.
  Rat   326 SGERKSQCVGWHSLESRWDRRACKMIQENSRQAICRCQPNKFFTSFSILMSPNTVESPVLTYITY 390

  Fly   210 TWKTVAIVISLICIILTISVYLYVEKLRNLHGKCFICYLASLFLGYF---FLVLNVWKYSSGF-- 269
            ....::|...:||:.:...|:..|.|..       |.||..|.:...   .|:.:||...:.|  
  Rat   391 IGLGISICSLIICLAIEALVWSQVTKTE-------ISYLRHLCIANIAVTLLMADVWFIVASFLS 448

  Fly   270 --------CVTAGFLGYFSVMAAFFW------LSVIGIHLRIKFSLASNCLHRLLPENPFRAYNL 320
                    ||||.|..:|..::.|||      |.:.|| |.:..:|..:||          ..:|
  Rat   449 GPIVHHNGCVTATFFVHFFYLSVFFWMLAKALLILYGI-LIVFHTLPKSCL----------VASL 502

  Fly   321 Y--AWGIPLIMTAITYTADQVVKNEKLRPRVGVGKNCWIYTGDMT-VMIYFYGPMLLLIAFNIIM 382
            :  .:|.||::..||....:..|. .|||..     ||: ..||| .::.|..|.|.::..|:|.
  Rat   503 FTVGYGCPLVIAVITLAVTEPGKG-YLRPEA-----CWL-NWDMTKALLAFVVPALAIVVVNLIT 560

  Fly   383 FVLSAIYIYNIKKNVKGLVHKQQTNQQINDQQMFAIFLRLFILMGLSWSFEI 434
            ..|   .|...::...|....|:....:...:..||   |..|:||:|.|.|
  Rat   561 VTL---VIIKTQRAAVGSSMFQEVRAIVRICKNIAI---LTPLLGLTWGFGI 606

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
mthl4NP_788394.1 Methuselah_N 23..201 CDD:284145 32/185 (17%)
7tm_4 213..>385 CDD:304433 50/193 (26%)
Adgrf2XP_017452241.2 GPS 330..377 CDD:413374 9/46 (20%)
7tm_GPCRs 382..628 CDD:421689 64/256 (25%)
TM helix 1 384..409 CDD:410628 3/24 (13%)
TM helix 2 424..446 CDD:410628 4/21 (19%)
TM helix 3 458..485 CDD:410628 9/26 (35%)
TM helix 4 499..519 CDD:410628 6/19 (32%)
TM helix 5 539..568 CDD:410628 9/31 (29%)
TM helix 6 584..610 CDD:410628 9/26 (35%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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