DRSC/TRiP Functional Genomics Resources

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Protein Alignment mthl4 and Adgrg3

DIOPT Version :9

Sequence 1:NP_788394.1 Gene:mthl4 / 36960 FlyBaseID:FBgn0034219 Length:517 Species:Drosophila melanogaster
Sequence 2:XP_038954076.1 Gene:Adgrg3 / 291854 RGDID:1305674 Length:574 Species:Rattus norvegicus


Alignment Length:373 Identity:76/373 - (20%)
Similarity:125/373 - (33%) Gaps:105/373 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly   172 WDKVELSK-----REYC-VQHLSFKDDSIRIAPHFCPLSSEHSRTWKTVAIVISLICII-LTISV 229
            ||....|.     |..| ..||:|  .::.:.|   .|....:||...::...|.:.:| |..::
  Rat   255 WDSHGCSTEPGDGRTVCRCDHLTF--FALL
LRP---TLDQATARTLTRISQAGSAVSMIFLAFTM 314

  Fly   230 YLYV-----------EKLRNLHGKCFICYLASLFLGYFFLVLNVWKYSSG---FC-VTAGFLGYF 279
            .|||           |....:|    :....||||.....::||...|.|   .| |.|....||
  Rat   315 VLYVAFRFSLQRFKSEDAPKIH----MALSTSLFLLNLTFLINVGSGSQGPPASCWVRAAIFHYF 375

  Fly   280 SVMAAFFWLSVIGIHLRIKFSLASNCLHRLLPENPFRAY--------NLYAWGIPLIMTAITYTA 336
             ::..|.|:.:...||            .||....|..|        :|..||:|:::.      
  Rat   376 -LLCVFTWMGLEAFHL------------YLLVIKVFNTYFGHYFLKLSLLGWGLPVLIV------ 421

  Fly   337 DQVVKNEKLRPRVGVGKN-------------------CWIYTGDMTVMIYFYGPMLLLIAFNIIM 382
                        :|||.:                   || :..:..:....:|..|:...|..::
  Rat   422 ------------IGVGSSNSYGVYTIRDQENRTSLELCW-FQKEPALYATVHGYFLVTFLFGAVV 473

  Fly   383 FVLSAIYIYNIKKNVKGLVHKQQTNQQINDQQMFAIFLRLFILMGLSWSFEILSFLLTKQQAWAR 447
            ..:.|..|:.:.....|....|.....:.       .|.|..|:|::|...:|:.|      ...
  Rat   474 LAMVAWKIFTLPSVTAGKGQGQTWKSVLT-------VLGLSSLVGMTWGLAVLTPL------GLS 525

  Fly   448 ALMVADYFNWSQGTIIFVLFILK--PSILKLIIAGGRQNLPGSHHNSR 493
            .:.:....|..||..||..||:.  |:......:.|...|..:|..|:
  Rat   526 TVYIFTLLNSLQGLFIFCWFIILYFPTQSTTTSSSGTARLDQAHSMSQ 573

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
mthl4NP_788394.1 Methuselah_N 23..201 CDD:284145 9/34 (26%)
7tm_4 213..>385 CDD:304433 41/214 (19%)
Adgrg3XP_038954076.1 GPS 244..282 CDD:396408 8/28 (29%)
7tm_GPCRs 292..551 CDD:421689 61/307 (20%)
TM helix 1 294..319 CDD:410628 6/24 (25%)
TM helix 2 333..355 CDD:410628 6/25 (24%)
TM helix 3 366..393 CDD:410628 8/39 (21%)
TM helix 4 406..426 CDD:410628 6/37 (16%)
TM helix 5 454..481 CDD:410628 4/26 (15%)
TM helix 6 495..522 CDD:410628 7/33 (21%)
TM helix 7 524..549 CDD:410628 7/24 (29%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4193
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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