Protein Alignment mthl4 and ADGRD1

DIOPT Version :9

• Sequence 1: NP_788394.1
• Gene: mthl4 / 36960
• FlyBaseID: FBgn0034219
• Length: 517
• Species: Drosophila melanogaster
• Sequence 2: NP_001317426.1
• Gene: ADGRD1 / 283383
• HGNCID: 19893
• Length: 906
• Species: Homo sapiens
• Alignment Length: 477
• Identity: 99/477 - (20%)
• Similarity: 159/477 - (33%)
• Gaps: 149/477 - (31%)

  Fly    42 YLYEGLLIPAHLTAEYDYKLLADDSKEKVASHVRGCACHLRPCIRFCCPQYQKMQKSKCYGDMSE 106
            :.|...:.|||               .|:|.     |.|.:.|:.|.......::.|.
Human   464 HYYLNNIWPAH---------------TKIAE-----AMHHQDCLLFATSHLISLEVSP------- 501

  Fly   107 DELNKHDPFVNVTLSDGSVVRRHFKEDLI-VQSDLAKPGCPRMY----FL----------NHELP 156
                  .|.::..||...::..|.|..|. .|...|.....|::    ||          ||...
Human   502 ------PPTLSQNLSGSPLITVHLKHRLTRKQHSEATNSSNRVFVYCAFLDFSSGEGVWSNHGCA 560

  Fly   157 ---GN------EFTLFENGSLLRHWDKVELSK-REYCVQHLSFKDDSIRIAPHFCPLSSEHSRTW 211
               ||      ..|...|.::|.....:||:: .:..:..:|:..         |.||
Human   561 LTRGNLTYSVCRCTHLTNFAILMQVVPLELARGHQVALSSISYVG---------CSLS------- 609

  Fly   212 KTVAIVISLICIILTISVYLYVEKLRN----LHGKCFICYLASLFLGYFFLVLNVWKYSSGF--C 270
                 |:.|:..::|.:|...|..:||    :|.......|.:.     .|:|..::...|.  |
Human   610 -----VLCLVATLVTFAVLSSVSTIRNQRYHIHANLSFAVLVAQ-----VLLLISFRLEPGTTPC 664

  Fly   271 VTAGFLGYFSVMAAFFWLSVIGIHLR---IKFSLASNCLHRLLPENPFRAYNLYAWGIPLI--MT 330
            .....|.::..::||.|:.|.|:||.   ||...:.:..||.        |....||.||:  :.
Human   665 QVMAVLLHYFFLSAFAWMLVEGLHLYSMVIKVFGSEDSKHRY--------YYGMGWGFPLLICII 721

  Fly   331 AITYTADQVVKNEKLRPRVGVGKNCWIYTGDMTVMIYFYGPMLLLIAFNI-----IMFVLSAIYI 390
            ::::..|.          .|...|||:......:.. |..|.|.:|..||     :..|:|.|..
Human   722 SLSFAMDS----------YGTSNNCWLSLASGAIWA-FVAPALFVIVVNIGILIAVTRVISQISA 775

  Fly   391 YNIKKNVKGLVHKQQTNQQINDQQMFAIFLR----LFILMGLSWSFEILSFLLTKQQAWARALMV 451
            .|.|      :|        .|...|.:..:    |..::|.||.|.:|        |.....:|
Human   776 DNYK------IH--------GDPSAFKLTAKAVAVLLPILGTSWVFGVL--------AVNGCAVV 818

  Fly   452 ADY----FNWSQGTIIFVLFIL 469
            ..|    .|..||..||:...|
Human   819 FQYMFATLNSLQGLFIFLFHCL 840

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mthl4	NP_788394.1	Methuselah_N	23..201	CDD:284145	32/183 (17%)
		7tm_4	213..>385	CDD:304433	41/187 (22%)
ADGRD1	NP_001317426.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4193
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810