Protein Alignment mthl4 and Adgrg2

DIOPT Version :9

• Sequence 1: NP_788394.1
• Gene: mthl4 / 36960
• FlyBaseID: FBgn0034219
• Length: 517
• Species: Drosophila melanogaster
• Sequence 2: XP_006528869.1
• Gene: Adgrg2 / 237175
• MGIID: 2446854
• Length: 1092
• Species: Mus musculus
• Alignment Length: 279
• Identity: 71/279 - (25%)
• Similarity: 116/279 - (41%)
• Gaps: 66/279 - (23%)

  Fly   218 ISLICIILTISVYLYVEKL-RNLHGKCFICYLASLFLGYFFLVLNVW--KYSS-GFCV-TAGFLG 277
            :|.|.:.:|:..|:..||: |:...|..|...|:|.|.....:|:.|  .|:: |||: .|.||.
Mouse   713 LSSIFLSVTLVTYIAFEKIRRDYPSKILIQLCAALLLLNLIFLLDSWIALYNTRGFCIAVAVFLH 777

  Fly   278 YFSVMAAFFWLSVIGIHLRIKFSLASNCLHRLLPENPFRAYNL----YAWGIPLIMTAITYTADQ 338
            || ::.:|.|:.:...|:.:......|..        .|.|.|    ..||||.::.:|..|
Mouse   778 YF-LLVSFTWMGLEAFHMYLALVKVFNTY--------IRKYILKFCIVGWGIPAVVVSIVLT--- 830

  Fly   339 VVKNEKLRP-RVGVGKN-----------CWIYTGDMTVMIYFY----GPMLLLIAFNIIMFVLSA 387
                  :.| ..|:|..           |||.:.     :.||    |...::...|:.||::..
Mouse   831 ------ISPDNYGIGSYGKFPNGTPDDFCWINSN-----VVFYITVVGYFCVIFLLNVSMFIVVL 884

  Fly   388 IYIYNIKKNVKGLVHKQQTNQQINDQQMFAIFLRLFILMGLSWSFEILSFLLTKQQAWARALMVA 452
            :.:..|||. |.|..:::|:  |.|.:..|   .|..|:|::|.|...        ||....:..
Mouse   885 VQLCRIKKK-KQLGAQRKTS--IQDLRSIA---GLTFLLGITWGFAFF--------AWGPVNVTF 935

  Fly   453 DY----FNWSQGTIIFVLF 467
            .|    ||..||..||:.:
Mouse   936 MYLFAIFNTLQGFFIFIFY 954

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mthl4	NP_788394.1	Methuselah_N	23..201	CDD:284145
		7tm_4	213..>385	CDD:304433	48/191 (25%)
Adgrg2	XP_006528869.1	Atrophin-1	<288..>423	CDD:367360
		PRK14948	<368..559	CDD:237862
		GPS	637..687	CDD:366827
		7tmB2_GPR64	700..969	CDD:320560	71/279 (25%)
		TM helix 1	703..727	CDD:320560	4/13 (31%)
		TM helix 2	737..758	CDD:320560	6/20 (30%)
		TM helix 3	770..792	CDD:320560	7/22 (32%)
		TM helix 4	812..828	CDD:320560	4/15 (27%)
		TM helix 5	858..881	CDD:320560	5/27 (19%)
		TM helix 6	904..929	CDD:320560	9/35 (26%)
		TM helix 7	933..958	CDD:320560	7/22 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4193
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810