Protein Alignment mthl4 and ADGRF2

DIOPT Version :9

• Sequence 1: NP_788394.1
• Gene: mthl4 / 36960
• FlyBaseID: FBgn0034219
• Length: 517
• Species: Drosophila melanogaster
• Sequence 2: NP_001355044.1
• Gene: ADGRF2 / 222611
• HGNCID: 18991
• Length: 708
• Species: Homo sapiens
• Alignment Length: 300
• Identity: 76/300 - (25%)
• Similarity: 130/300 - (43%)
• Gaps: 55/300 - (18%)

  Fly   167 SLLRHWDK------VELSKREYCVQHLS--FKDDSIRIAPHFCPLSSEHSRTWKT-VAIVISLIC 222
            |:...||:      .|.|::..|....|  |...||.::||   :......|:.| |.:.||:..
Human   399 SVENRWDQQACKMIQENSQQAVCKCRPSKLFTSFSILMSPH---ILESLILTYITYVGLGISICS 460

  Fly   223 IILTISVYLYV------EKLRNLHGKCFICYLASLFLGYFFLVLNVWKYSSGF----------CV 271
            :||.:|:.:.|      .::..|...|.:...|:|      |:.:||...:.|          ||
Human   461 LILCLSIEVLVWSQVTKTEITYLRHVCIVNIAATL------LMADVWFIVASFLSGPITHHKGCV 519

  Fly   272 TAGFLGYFSVMAAFFWLSVIGIHLRIKFSLASNCLHRLLPENPFRAYNLYA--WGIPLIMTAITY 334
            .|.|..:|..::.|||:  :...|.|.:.:.  .:...||::...| :|::  :|.||.:.|||.
Human   520 AATFFVHFFYLSVFFWM--LAKALLILYGIM--IVFHTLPKSVLVA-SLFSVGYGCPLAIAAITV 579

  Fly   335 TADQVVKNEKLRPRVGVGKNCWIYTGDMT-VMIYFYGPMLLLIAFNIIMFVLSAIYIYNIKKNVK 398
            .|.:..|. .|||.:     ||: ..||| .::.|..|.|.::..|:|...|   .|...::...
Human   580 AATEPGKG-YLRPEI-----CWL-NWDMTKALLAFVIPALAIVVVNLITVTL---VIVKTQRAAI 634

  Fly   399 GLVHKQQTNQQINDQQMFAIFLRLFILMGLSWSFEILSFL 438
            |....|:....:...:..||   |..|:||:|.|.:.:.:
Human   635 GNSMFQEVRAIVRISKNIAI---LTPLLGLTWGFGVATVI 671

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mthl4	NP_788394.1	Methuselah_N	23..201	CDD:284145	12/41 (29%)
		7tm_4	213..>385	CDD:304433	51/191 (27%)
ADGRF2	NP_001355044.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4193
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810