Protein Alignment mthl4 and ADGRF4

DIOPT Version :9

• Sequence 1: NP_788394.1
• Gene: mthl4 / 36960
• FlyBaseID: FBgn0034219
• Length: 517
• Species: Drosophila melanogaster
• Sequence 2: NP_001334784.1
• Gene: ADGRF4 / 221393
• HGNCID: 19011
• Length: 695
• Species: Homo sapiens
• Alignment Length: 341
• Identity: 73/341 - (21%)
• Similarity: 129/341 - (37%)
• Gaps: 89/341 - (26%)

  Fly   170 RHWDKVELSKREYCVQHLSFKDD------SIRIAPHFCPLSSEHSRTWK----------TVAIVI 218
            |.||:      :.|...|..:::      ...:...|..|.|..|.|.|          :|:|:.
Human   357 RRWDE------KACQMMLDIRNEVKCRCNYTSVVMSFSILMSSKSMTDKVLDYITCIGLSVSILS 415

  Fly   219 SLICIILTISVY--LYVEKLRNLHGKCFICYLASLFLGYFFLVLNVW----------KYSSGFCV 271
            .::|:|:..:|:  :.|.::..:...|.:....||      |..|||          ......||
Human   416 LVLCLIIEATVWSRVVVTEISYMRHVCIVNIAVSL------LTANVWFIIGSHFNIKAQDYNMCV 474

  Fly   272 TAGFLGYFSVMAAFFW------LSVIGIHLRIKFSLASNCLHRLLPENPFRAYNLYAWGIPLIMT 330
            ...|..:|..::.|||      |.:.||.:         ...|::............:|.|||:
Human   475 AVTFFSHFFYLSLFFWMLFKALLIIYGILV---------IFRRMMKSRMMVIGFAIGYGCPLII- 529

  Fly   331 AITYTADQVVKNEK--LRPRVGVGKNCWIYTGDMTVMIYFYGPMLLLIAFNIIMFVLSAIYIYNI 393
            |:|..|  :.:.||  :||..     ||:...:...::.|..|..:::|.|:|:.::.|
Human   530 AVTTVA--ITEPEKGYMRPEA-----CWLNWDNTKALLAFAIPAFVIVAVNLIVVLVVA------ 581

  Fly   394 KKNVKGLVHKQQTNQQINDQQMFAIFLR-------LFILMGLSWSFEILSFL----LTKQQAWAR 447
                   |:.|:.:...:..|...|.:|       |..|:||:|.|.|.:.:    ||....:|.
Human   582 -------VNTQRPSIGSSKSQDVVIIMRISKNVAILTPLLGLTWGFGIATLIEGTSLTFHIIFAL 639

  Fly   448 ALMVADYFNWSQGTII 463
            ......:|....|||:
Human   640 LNAFQGFFILLFGTIM 655

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mthl4	NP_788394.1	Methuselah_N	23..201	CDD:284145	5/36 (14%)
		7tm_4	213..>385	CDD:304433	42/191 (22%)
ADGRF4	NP_001334784.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	674..695

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4193
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810