DRSC/TRiP Functional Genomics Resources

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Protein Alignment mthl4 and Adgrg1

DIOPT Version :9

Sequence 1:NP_788394.1 Gene:mthl4 / 36960 FlyBaseID:FBgn0034219 Length:517 Species:Drosophila melanogaster
Sequence 2:XP_006530743.1 Gene:Adgrg1 / 14766 MGIID:1340051 Length:718 Species:Mus musculus


Alignment Length:288 Identity:62/288 - (21%)
Similarity:107/288 - (37%) Gaps:71/288 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly   214 VAIVISLICIILTISVYLYV-EKLRNLHGKCFICYLASLFLGYFFLVLN---VWKYSSGFCVTAG 274
            |..|||.:..:.||:.||.. .|.|:...|..:..|:::||.....:|:   ....|...|.|:.
Mouse   440 VGCVISALACVFTIAAYLCSRRKSRDYTIKVHMNLLSAVFLLDVSFLLSEPVALTGSEAACRTSA 504

  Fly   275 FLGYFSVMAAFFWLSVIGIHLRIKFSLASNCLHRLLPENPFRAY--------NLYAWGIPLIMTA 331
            ...:||::|...|:.:.|.:           |:||:.| .|..|        ::..||.|:.:..
Mouse   505 MFLHFSLLACLSWMGLEGYN-----------LYRLVVE-VFGTYVPGYLLKLSIVGWGFPVFLVT 557

  Fly   332 ITYTADQVVKN--------EKLRPRVGVGKNCWIYTGDMTVMIYFYGPMLLLIAFNIIMFVLSAI 388
            :....|  |.|        .:...||.....||| ...:...:...|...|:..||:.|.....:
Mouse   558 LVALVD--VNNYGPIILAVRRTPERVTYPSMCWI-RDSLVSYVTNLGLFSLVFLFNLAMLATMVV 619

  Fly   389 YIYNIKKNVKGLVHKQQTNQQINDQQMFAIFLRLFILMGLSWSFEILSFLLTKQQAWARALMVAD 453
            .|..::.:.:...|             ....|.|.:::||.|                 ||:   
Mouse   620 QILRLRPHSQNWPH-------------VLTLLGLSLVLGLPW-----------------ALV--- 651

  Fly   454 YFNWSQGT---IIFVLFILKPSILKLII 478
            :|:::.||   :|..||.:..|....:|
Mouse   652 FFSFASGTFQLVILYLFSIITSFQGFLI 679

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
mthl4NP_788394.1 Methuselah_N 23..201 CDD:284145
7tm_4 213..>385 CDD:304433 45/190 (24%)
Adgrg1XP_006530743.1 PLL 60..193 CDD:376013
GAIN_A 204..251 CDD:376045
GPS 376..419 CDD:366827
7tm_GPCRs 431..698 CDD:391938 62/288 (22%)
TM helix 1 433..458 CDD:341315 7/17 (41%)
TM helix 2 468..490 CDD:341315 5/21 (24%)
TM helix 3 501..528 CDD:341315 7/37 (19%)
TM helix 4 541..561 CDD:341315 3/19 (16%)
TM helix 5 592..621 CDD:341315 5/28 (18%)
TM helix 6 629..656 CDD:341315 9/59 (15%)
TM helix 7 662..687 CDD:341315 5/18 (28%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4193
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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