Protein Alignment mthl4 and adgrg2a

DIOPT Version :9

• Sequence 1: NP_788394.1
• Gene: mthl4 / 36960
• FlyBaseID: FBgn0034219
• Length: 517
• Species: Drosophila melanogaster
• Sequence 2: XP_005162818.2
• Gene: adgrg2a / 101882832
• ZFINID: ZDB-GENE-140106-206
• Length: 2289
• Species: Danio rerio
• Alignment Length: 520
• Identity: 114/520 - (21%)
• Similarity: 205/520 - (39%)
• Gaps: 149/520 - (28%)

  Fly    49 IPAHLTAEYDYKLLADDSKEKVASHVRGCACHLRPCIRFCCPQYQKMQKSKCYGD--MSEDELNK 111
            :||.||..      ....::|:||.|                |:...|||..:.|  :::.:||.
Zfish  1792 LPASLTEN------LSPEEQKMASRV----------------QFTFYQKSTFFQDANLNQKKLNS 1834

  Fly   112 HDPFVNVTLSDGSVVRRHFKEDLIVQSDLAKPGCPRMYFLNHELPGNEFTL-------------- 162
            :  .:..::::.|:  |:.:|::                        ||||
Zfish  1835 Y--ILGSSVANLSI--RNLRENI------------------------EFTLMNKQPVAGNYVAVC 1871

  Fly   163 ----FENGSLLRHWDKVELSKREYC-VQHLSFKDDSIRIAPHFCPLS-----SEHSRTWKTVAIV 217
                |:....|..|:      |:.| |.:.|.::::|....|....:     |:...|.:..|.:
Zfish  1872 VFWDFDKNEGLGGWN------RDGCSVMNSSTENETICSCSHLTSFAVLMDISQQGVTDRMQATI 1930

  Fly   218 ISLICII----------LTISVYLYVEKL-RNLHGKCFI--CYLASLFLGYFFLV---LNVWKYS 266
            ::.|..|          :|:..||..:|: |::..|..|  |: |.|||...||:   |.::..:
Zfish  1931 LTFISYIGCGVSAIFLSVTLLTYLSFDKIRRDIPSKILIHLCF-ALLFLNLVFLLDSWLALYTDA 1994

  Fly   267 SGFCV-TAGFLGYFSVMAAFFWLSVIGIHLRIKF-SLASNCLHRLLPENPFRAYNLYAWGIPLIM 329
            .|.|: ||.||.|| ::.:|.|:.:..:|:.:.. .:.:|.:.|.:.:     ::|..||:||.:
Zfish  1995 VGLCISTAFFLHYF-LLVSFTWMGLEALHMYLAIVKVFNNFMSRYMLK-----FSLIGWGVPLAV 2053

  Fly   330 TAITYTADQVVKNEKLRPRVGVGK--------NCWIYTGD---MTVMIYFYGPMLLLIAFNIIMF 383
            ..|.     :..|:.....:..||        .||:....   :.|:.||    .::...|:.||
Zfish  2054 VIIV-----IAINKDNYGLISYGKFSDGTTDDFCWLKNSTAFYVAVVAYF----CIIFVLNLAMF 2109

  Fly   384 VLSAIYIYNIKKNVKGLVHKQQTNQQINDQQMFAIFLRLFILMGLSWSFEILSFLLTKQQAWARA 448
            |:..:::..||:...   |..|....:.|.:..|   .|..|:||:|.|...        ||...
Zfish  2110 VVVMVHLRRIKRRNP---HNNQYRSGVQDLRSIA---GLTFLLGLTWGFAFF--------AWGPV 2160

  Fly   449 LMVADY----FNWSQGTIIFVLF-ILKPSILK---LIIAGGRQNLPGSHHNSRSKAARYNSTHTA 505
            .:...|    ||..||..|||.. .||.::.|   :.:..|...||.:...||:.....|:..|:
Zfish  2161 NLAFTYLFSIFNCLQGFFIFVFHCALKENVRKEWRIYLCCGSLRLPENSEWSRTATQSQNTKKTS 2225

  Fly   506  505
            Zfish  2226  2225

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mthl4	NP_788394.1	Methuselah_N	23..201	CDD:284145	31/172 (18%)
		7tm_4	213..>385	CDD:304433	48/200 (24%)
adgrg2a	XP_005162818.2	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4193
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810