DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Bap55 and Actl6a

DIOPT Version :9

Sequence 1:	NP_611209.1	Gene:	Bap55 / 36956	FlyBaseID:	FBgn0025716	Length:	425	Species:	Drosophila melanogaster
Sequence 2:	NP_062647.2	Gene:	Actl6a / 56456	MGIID:	1861453	Length:	429	Species:	Mus musculus

Alignment Length:	442	Identity:	240/442 - (54%)
Similarity:	316/442 - (71%)	Gaps:	30/442 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSGGTMLYGGDEIGALVFDPGHHSLRVGYAQEDSPKAEIPSVVGIGAAPETNLDPETKTDNNATP 65
            ||||  :|||||:||||||.|.:::|.|||.||.||.:.|:.:|:          ..:.|:.:|.
Mouse     1 MSGG--VYGGDEVGALVFDIGSYTVRAGYAGEDCPKVDFPTAIGV----------VLERDDGSTM 53

  Fly    66 NNADQRK-------FYVDTNYVTVPRSNMEVQTYMKDGMIDNWDLFEKVIDYAYANVIQSEPEYH 123
            ...|..|       :|:|||.:.|||.|||..:.:|:||:::||.|:.::|:.|...::||...|
Mouse    54 MEIDGDKGKQGGPTYYIDTNALRVPRENMEAISPLKNGMVEDWDSFQAILDHTYKMHVKSEASLH 118

  Fly   124 PVLFSEASWNVRNNREKLTELMFEKYNVPAFFLVKNAVLAAFSSGRATALVVDSGATHTSAVPVH 188
            |||.|||.||.|..||||||||||.|::|||||.|.|||.||::||:|.|::|||||||:|:|||
Mouse   119 PVLMSEAPWNTRAKREKLTELMFEHYSIPAFFLCKTAVLTAFANGRSTGLILDSGATHTTAIPVH 183

  Fly   189 EGYVLSQAVVKSPLGGDFLSRQCRQHLEKHGIDLSPVYKIASKDVVKERDNGRFTLR-KLPENLT 252
            :||||.|.:|||||.|||::.|||:..::..|:|.|.|.||||:.|:|.....:..: |||: :|
Mouse   184 DGYVLQQGIVKSPLAGDFITMQCRELFQEMNIELIPPYMIASKEAVREGSPANWKRKEKLPQ-VT 247

  Fly   253 QSWQNYMLQLMMQDFQMNVLQVLENPFDERVAAQIPTVHYEFPNGYHQDFGSERFKIAESLFD-- 315
            :||.|||...::||||.:||||.::.:||:||||:|||||||||||:.|||:||.||.|.|||
Mouse   248 RSWHNYMCNCVIQDFQASVLQVSDSTYDEQVAAQMPTVHYEFPNGYNCDFGAERLKIPEGLFDPS 312

  Fly   316 -------NAMLGAGQLASTSVGMCDADVRLSLFGSVVVTGGNTLLQGFPERLNRDLQLRAPSNTR 373
                   |.|||...:.:|||||||.|:|..|:|||:|.|||||:|.|.:||||:|..:.|.:.|
Mouse   313 NVKGLSGNTMLGVSHVVTTSVGMCDIDIRPGLYGSVIVAGGNTLIQSFTDRLNRELSQKTPPSMR 377

  Fly   374 LKMISANGSVERRFGAWIGGSILASIGTFQQMWISSQEYEEAGKSQVERKCP 425
            ||:|:.|.:|||||.:|||||||||:|||||||||.|||||.||..||||||
Mouse   378 LKLIANNTTVERRFSSWIGGSILASLGTFQQMWISKQEYEEGGKQCVERKCP 429

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Bap55	NP_611209.1	Actin	13..425	CDD:394979	229/428 (54%)
Actl6a	NP_062647.2	Actin	11..429	CDD:394979	229/428 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	482	1.000	Domainoid score	I409
eggNOG	1	0.900	-	-		E1_COG5277
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H55811
Inparanoid	1	1.050	493	1.000	Inparanoid score	I1388
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55702
OrthoDB	1	1.010	-	-		D649708at2759
OrthoFinder	1	1.000	-	-		FOG0001878
OrthoInspector	1	1.000	-	-		otm43369
orthoMCL	1	0.900	-	-		OOG6_102754
Panther	1	1.100	-	-	O	PTHR11937
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4301
SonicParanoid	1	1.000	-	-		X1579
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.870