DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Bap55 and acte1

DIOPT Version :9

Sequence 1:	NP_611209.1	Gene:	Bap55 / 36956	FlyBaseID:	FBgn0025716	Length:	425	Species:	Drosophila melanogaster
Sequence 2:	NP_001002074.2	Gene:	acte1 / 415164	ZFINID:	ZDB-GENE-040625-46	Length:	377	Species:	Danio rerio

Alignment Length:	419	Identity:	144/419 - (34%)
Similarity:	220/419 - (52%)	Gaps:	52/419 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 DEIGALVFDPGHHSLRVGYAQEDSPKAEIPSVVGIGAAPETNLDPETKTDNNATPNNADQRKFYV 75
            :|..|||.|.|...::.|:|.:|:|:|..||:||             :..:........|:..||
Zfish     5 EETTALVCDNGSGLVKAGFAGDDAPRAVFPSIVG-------------RPRHQGVMVGMGQKDSYV 56

  Fly    76 DTNYVTVPRSNMEVQTYMKDGMIDNWDLFEKVIDYAYANVIQSEPEYHPVLFSEASWNVRNNREK 140
            . :.....|..:.::..::.|:|.|||..||:..:.:.|.::..||.||||.:||..|.:.||||
Zfish    57 G-DEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREK 120

  Fly   141 LTELMFEKYNVPAFFLVKNAVLAAFSSGRATALVVDSGATHTSAVPVHEGYVLSQAVVKSPLGGD 205
            :|::|||.:||||.::...|||:.::|||.|.:|:|:|...|..|||:|||.|..|:::..|.|.
Zfish   121 MTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDAGDGVTHNVPVYEGYALPHAIMRLDLAGR 185

  Fly   206 FLSRQCRQHLEKHGIDLSPVYKIASKDVVKERDNGRFTLRKLPENLTQSWQNYMLQLMMQDFQMN 270
            .|:....:.|.:.|...   ...|.:::|          |.:.|.|.         .:..||
Zfish   186 DLTDYLMKILTERGYSF---VTTAEREIV----------RDIKEKLC---------YVALDF--- 225

  Fly   271 VLQVLENPFDERVAAQIPTVHYEFPNGYHQDFGSERFKIAESLFDNAMLG---AGQLASTSVGM- 331
                 ||......::......||.|:|.....|:|||:..|:||..:.:|   ||...:|..|:
Zfish   226 -----ENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNGIM 285

  Fly   332 -CDADVRLSLFGSVVVTGGNTLLQGFPERLNRDLQLRAPSNTRLKMISANGSVERRFGAWIGGSI 395
             ||.|:|..|:.:.|::||.|:..|..:|:.:::...|||..::|||:   ..||::..||||||
Zfish   286 KCDIDIRKDLYANNVLSGGTTMYPGIGDRMQKEITALAPSTMKIKMIA---PPERKYSVWIGGSI 347

  Fly   396 LASIGTFQQMWISSQEYEEAGKSQVERKC 424
            |||:.||||||||..||||||.|.|.|||
Zfish   348 LASLSTFQQMWISKDEYEEAGPSIVHRKC 376

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Bap55	NP_611209.1	Actin	13..425	CDD:394979	143/417 (34%)
acte1	NP_001002074.2	NBD_sugar-kinase_HSP70_actin	4..377	CDD:418402	144/419 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5277
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D649708at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.820