DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Bap55 and actr2a

DIOPT Version :9

Sequence 1:	NP_611209.1	Gene:	Bap55 / 36956	FlyBaseID:	FBgn0025716	Length:	425	Species:	Drosophila melanogaster
Sequence 2:	XP_021326108.1	Gene:	actr2a / 406820	ZFINID:	ZDB-GENE-040426-2894	Length:	399	Species:	Danio rerio

Alignment Length:	432	Identity:	105/432 - (24%)
Similarity:	181/432 - (41%)	Gaps:	72/432 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 LVFDPGHHSLRVGYAQEDSPKAEIPSVVGIGAAPETNLDPETKTDNNATPNNAD----QRKFYVD 76
            :|.|.|...::.|||..:.|:...|::||......|           |...|.:    :|...:.
Zfish     9 VVCDNGTGFVKCGYAGSNFPEHIFPALVGRPIIRST-----------AKVGNIEIKDYRRMDLMV 62

  Fly    77 TNYVTVPRSNMEVQTYMKDGMIDNWDLFEKVIDYAYA-NVIQSEPEYHPVLFSEASWNVRNNREK 140
            .:..:..||.:||...|::|::.|||..:.:.||.:. ..:..:.....:|.:|...|...||||
Zfish    63 GDEASELRSMLEVNYPMENGIVRNWDDMKHLWDYTFGPEKLNIDSRNCKILLTEPPMNPTKNREK 127

  Fly   141 LTELMFEKYNVPAFFLVKNAVLAAFSSGRATALVVDSGATHTSAVPVHEGYVLSQAVVKSPLGGD 205
            :.|:|||.|.....::...|||..::.|..|.:|||||...|...||:||:.|.....:..:.|.
Zfish   128 IIEVMFETYQFSGVYIAIQAVLTLYAQGLLTGVVVDSGDGVTHICPVYEGFSLPHLTRRLDIAGR 192

  Fly   206 FLSRQ------CRQHLEKHGIDLSPVYKIASKDVVKERDNGRFTLRKLPENLTQSWQNYMLQLMM 264
            .::|.      .|.:...|..|..                   |:|.:.|.|  .:..|.:: ..
Zfish   193 DITRYLIKLLLLRGYAFNHSADFE-------------------TVRMMKEKL--CYVGYNIE-QE 235

  Fly   265 QDFQMNVLQVLENPFDERVAAQIPTVHYEFPNGYHQDFGSERFKIAESLFDNAML-----GAGQL 324
            |...:....::|:              |..|:|.....|.|||:..|:||...::     |..:|
Zfish   236 QKLALETTVLVES--------------YTLPDGRVIKVGGERFEAPEALFQPHLINVEGVGVAEL 286

  Fly   325 ASTSVGMCDADVRLSLFGSVVVTGGNTLLQGFPERLNRDLQ-------LRAPSNTRLKM-ISANG 381
            ...::...|.|.|...:..:|::||:|:..|.|.||.|:|:       |:...:...|. |....
Zfish   287 LFNTIQAADIDTRAEFYKHIVLSGGSTMYPGLPSRLERELKQLYLERVLKGDVDKLSKFKIRIED 351

  Fly   382 SVERRFGAWIGGSILASI-GTFQQMWISSQEYEEAGKSQVER 422
            ...|:...::||::||.| ......|::.:||:|.|...:|:
Zfish   352 PPRRKHMVFLGGAVLADIMKDKDNFWMTREEYQEKGTRVLEK 393

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Bap55	NP_611209.1	Actin	13..425	CDD:394979	105/432 (24%)
actr2a	XP_021326108.1	ACTIN	6..393	CDD:214592	104/430 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5277
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D649708at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820