DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Bap55 and Actr3b

DIOPT Version :9

Sequence 1:	NP_611209.1	Gene:	Bap55 / 36956	FlyBaseID:	FBgn0025716	Length:	425	Species:	Drosophila melanogaster
Sequence 2:	NP_001178789.1	Gene:	Actr3b / 362298	RGDID:	1565759	Length:	418	Species:	Rattus norvegicus

Alignment Length:	439	Identity:	112/439 - (25%)
Similarity:	189/439 - (43%)	Gaps:	78/439 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 VFDPGHHSLRVGYAQEDSPKAEIPSVVGIGAAPETNLDPETKTDNNATPNNADQRKFYVDTNYVT 81
            |.|.|....::|||....|:..|||.:.|..:.:. :|...:    ......|...|::....:.
  Rat     9 VVDCGTGYTKLGYAGNTEPQFIIPSCIAIRESAKV-VDQAQR----RVLRGVDDLDFFIGDEAID 68

  Fly    82 VPRSNMEVQTY-----MKDGMIDNWDLFEKVIDYAYANVIQSEPEYHPVLFSEASWNVRNNREKL 141
            .|       ||     ::.|::::|||.|:.::......:::|||.|..|.:|...|...|||.|
  Rat    69 KP-------TYATKWPIRHGIVEDWDLMERFMEQVVFKYLRAEPEDHYFLMTEPPLNTPENREYL 126

  Fly   142 TELMFEKYNVPAFFLVKNAVLAAFSSGRA--------TALVVDSGATHTSAVPVHEGYVLSQAVV 198
            .|:|||.:|||..::...||||..:|..:        |.:|:|||...|..:||.||||:...:.
  Rat   127 AEIMFESFNVPGLYIAVQAVLALAASWTSRQVGERTLTGIVIDSGDGVTHVIPVAEGYVIGSCIK 191

  Fly   199 KSPLGGDFLSRQCRQHLEKHGIDLSPVYKIASKDVVKERDNGRFTLRKLPENLTQSWQNYMLQLM 263
            ..|:.|..::...:|.|.:..:.:.|...:.:...:||:                  ..|:...:
  Rat   192 HIPIAGRDITYFIQQLLREREVGIPPEQSLETAKAIKEK------------------YCYICPDI 238

  Fly   264 MQDFQMNVLQVLENPFDERVAAQIPTVHYEFPNGYHQ-----DFGSERFKIAESLFDNAMLGAGQ 323
            :::|       .:...|.|...:    .|...|..:|     |.|.|||...|..|.........
  Rat   239 VKEF-------AKYDVDPRKWIK----QYTGINAINQRKFIIDVGYERFLGPEIFFHPEFANPDF 292

  Fly   324 LASTS------VGMCDADVRLSLFGSVVVTGGNTLLQGFPERLNRDLQLRAPSNTRLKMISANGS 382
            :.|.|      :..|..|||..|:.::|::||:|:.:.|..||.|||:....:..:|....:.|.
  Rat   293 MESISDVVDEVIQNCPIDVRRPLYKNIVLSGGSTMFRDFGRRLQRDLKRVVDARLKLSQELSGGR 357

  Fly   383 VE-------------RRFGAWIGGSILASIGTFQQMWISSQEYEEAGKS 418
            ::             :|:..|.|||:|||...|.|:..:.::|||.|.|
  Rat   358 IKPKPVEVQVITHHMQRYAVWFGGSMLASTPEFFQVCHTKKDYEEYGPS 406

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Bap55	NP_611209.1	Actin	13..425	CDD:394979	112/439 (26%)
Actr3b	NP_001178789.1	PTZ00280	2..417	CDD:240343	112/439 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5277
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D649708at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910