DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Bap55 and acta2

DIOPT Version :9

Sequence 1:	NP_611209.1	Gene:	Bap55 / 36956	FlyBaseID:	FBgn0025716	Length:	425	Species:	Drosophila melanogaster
Sequence 2:	NP_997785.2	Gene:	acta2 / 322509	ZFINID:	ZDB-GENE-030131-1229	Length:	377	Species:	Danio rerio

Alignment Length:	419	Identity:	141/419 - (33%)
Similarity:	219/419 - (52%)	Gaps:	52/419 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 DEIGALVFDPGHHSLRVGYAQEDSPKAEIPSVVGIGAAPETNLDPETKTDNNATPNNADQRKFYV 75
            :|..|||.|.|....:.|:|.:|:|:|..||:||             :..:........|:..||
Zfish     5 EESTALVCDNGSGLCKAGFAGDDAPRAVFPSIVG-------------RPRHQGVMVGMGQKDSYV 56

  Fly    76 DTNYVTVPRSNMEVQTYMKDGMIDNWDLFEKVIDYAYANVIQSEPEYHPVLFSEASWNVRNNREK 140
            . :.....|..:.::..::.|:|.|||..||:..:::.|.::..||.||.|.:||..|.:.||||
Zfish    57 G-DEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHSFYNELRVAPEEHPTLLTEAPLNPKANREK 120

  Fly   141 LTELMFEKYNVPAFFLVKNAVLAAFSSGRATALVVDSGATHTSAVPVHEGYVLSQAVVKSPLGGD 205
            :|::|||.:||||.::...|||:.::|||.|.:|:|||...|..||::|||.|..|:::..|.|.
Zfish   121 MTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGR 185

  Fly   206 FLSRQCRQHLEKHGIDLSPVYKIASKDVVKERDNGRFTLRKLPENLTQSWQNYMLQLMMQDFQMN 270
            .|:....:.|.:.|...   ...|.:::|          |.:.|.|.         .:..||
Zfish   186 DLTDYLMKILTERGYSF---VTTAEREIV----------RDIKEKLC---------YVALDF--- 225

  Fly   271 VLQVLENPFDERVAAQIPTVHYEFPNGYHQDFGSERFKIAESLFDNAMLG---AG--QLASTSVG 330
                 ||......::......||.|:|.....|:|||:..|:||..:.:|   ||  :....|:.
Zfish   226 -----ENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIM 285

  Fly   331 MCDADVRLSLFGSVVVTGGNTLLQGFPERLNRDLQLRAPSNTRLKMISANGSVERRFGAWIGGSI 395
            .||.|:|..|:.:.|::||.|:..|..:|:.:::...|||..::|:|:   ..||::..||||||
Zfish   286 KCDIDIRKDLYANNVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIA---PPERKYSVWIGGSI 347

  Fly   396 LASIGTFQQMWISSQEYEEAGKSQVERKC 424
            |||:.||||||||.|||:|||.|.|.|||
Zfish   348 LASLSTFQQMWISKQEYDEAGPSIVHRKC 376

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Bap55	NP_611209.1	Actin	13..425	CDD:394979	140/417 (34%)
acta2	NP_997785.2	PTZ00281	4..377	CDD:173506	141/419 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D649708at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920