DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Bap55 and Actbl2

DIOPT Version :9

Sequence 1:	NP_611209.1	Gene:	Bap55 / 36956	FlyBaseID:	FBgn0025716	Length:	425	Species:	Drosophila melanogaster
Sequence 2:	NP_001099879.1	Gene:	Actbl2 / 294732	RGDID:	1309504	Length:	376	Species:	Rattus norvegicus

Alignment Length:	419	Identity:	135/419 - (32%)
Similarity:	219/419 - (52%)	Gaps:	52/419 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 DEIGALVFDPGHHSLRVGYAQEDSPKAEIPSVVGIGAAPETNLDPETKTDNNATPNNADQRKFYV 75
            ||:||||.|.|....:.|:..:|:|:|..||:||             :..:........|:..||
  Rat     4 DELGALVVDNGSGMCKAGFGGDDAPRAVFPSMVG-------------RPRHQGVMVGMGQKDCYV 55

  Fly    76 DTNYVTVPRSNMEVQTYMKDGMIDNWDLFEKVIDYAYANVIQSEPEYHPVLFSEASWNVRNNREK 140
            . :.....|..:.::..::.|::.|||..||:..:.:.|.::..|:.||:|.:||..|.:.||||
  Rat    56 G-DEAQSKRGILTLKYPIEHGVVTNWDDMEKIWYHTFYNELRVAPDEHPILLTEAPLNPKINREK 119

  Fly   141 LTELMFEKYNVPAFFLVKNAVLAAFSSGRATALVVDSGATHTSAVPVHEGYVLSQAVVKSPLGGD 205
            :|::|||.:|.||.::...|||:.::|||.|..|:|||...|..||::|||.|...:::..|.|.
  Rat   120 MTQIMFEAFNTPAMYVAIQAVLSLYASGRTTGNVMDSGDGVTHTVPIYEGYALPHGILRLDLAGR 184

  Fly   206 FLSRQCRQHLEKHGIDLSPVYKIASKDVVKERDNGRFTLRKLPENLTQSWQNYMLQLMMQDFQMN 270
            .|:....:.|.:.|.:.:..   |.:::|          |.:.|.|.         .:..||:..
  Rat   185 DLTDYLMKILTERGYNFTTT---AEREIV----------RDVKEKLC---------YVALDFEQE 227

  Fly   271 VLQVLENPFDERVAAQIPTVHYEFPNGYHQDFGSERFKIAESLFDNAML-----GAGQLASTSVG 330
            ::....:...||        .||.|:|.....|:|||:..|::|..:.|     |..:....|:.
  Rat   228 MVTAAASSSLER--------SYELPDGQVITIGNERFRCPEAIFQPSFLGIESRGIHETTFNSIM 284

  Fly   331 MCDADVRLSLFGSVVVTGGNTLLQGFPERLNRDLQLRAPSNTRLKMISANGSVERRFGAWIGGSI 395
            .||.|:|..|:.:.|::||:|:..|..:|:.:::...|||..::|:|:   ..||::..||||||
  Rat   285 KCDVDIRKDLYANTVLSGGSTMYPGIADRMQKEIVTLAPSTMKIKIIA---PPERKYSVWIGGSI 346

  Fly   396 LASIGTFQQMWISSQEYEEAGKSQVERKC 424
            |||:.||||||||.|||:|||...|.|||
  Rat   347 LASLSTFQQMWISKQEYDEAGPPIVHRKC 375

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Bap55	NP_611209.1	Actin	13..425	CDD:394979	133/417 (32%)
Actbl2	NP_001099879.1	NBD_sugar-kinase_HSP70_actin	1..376	CDD:302596	135/419 (32%)
Actbl2	NP_001099879.1	ACTIN	8..376	CDD:214592	132/415 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5277
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D649708at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820