DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Bap55 and Actl6b

DIOPT Version :9

Sequence 1:	NP_611209.1	Gene:	Bap55 / 36956	FlyBaseID:	FBgn0025716	Length:	425	Species:	Drosophila melanogaster
Sequence 2:	XP_006249182.1	Gene:	Actl6b / 288563	RGDID:	1307763	Length:	444	Species:	Rattus norvegicus

Alignment Length:	454	Identity:	244/454 - (53%)
Similarity:	322/454 - (70%)	Gaps:	39/454 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSGGTMLYGGDEIGALVFDPGHHSLRVGYAQEDSPK------------------AEIPSVVGIGA 47
            ||||  :|||||:||||||.|..|:|.|||.||.||                  |:.|:.||:.|
  Rat     1 MSGG--VYGGDEVGALVFDIGSFSVRAGYAGEDCPKVSLPVPSPYPRGSDTLCQADFPTTVGLLA 63

  Fly    48 APE-TNLDPETKTDNNATPNNADQRKFYVDTNYVTVPRSNMEVQTYMKDGMIDNWDLFEKVIDYA 111
            |.| ..|:.|.:.:...       :.|::|||.:.|||...||.:.:|:|||::|:.|..::|:.
  Rat    64 AEEGGGLELEGEKEKKG-------KIFHIDTNALHVPRDGAEVMSPLKNGMIEDWECFRAILDHT 121

  Fly   112 YANVIQSEPEYHPVLFSEASWNVRNNREKLTELMFEKYNVPAFFLVKNAVLAAFSSGRATALVVD 176
            |:..::|||..||||.|||.||.|..||||||||||:||:|||||.|.|||.||::||:|.||:|
  Rat   122 YSKHVKSEPNLHPVLMSEAPWNTRAKREKLTELMFEQYNIPAFFLCKTAVLTAFANGRSTGLVLD 186

  Fly   177 SGATHTSAVPVHEGYVLSQAVVKSPLGGDFLSRQCRQHLEKHGIDLSPVYKIASKDVVKERDNGR 241
            ||||||:|:|||:||||.|.:|||||.|||:|.|||:..::..||:.|.|.||:|:.|:|.....
  Rat   187 SGATHTTAIPVHDGYVLQQGIVKSPLAGDFISMQCRELFQEMAIDIIPPYMIAAKEPVREGAPPN 251

  Fly   242 FTLR-KLPENLTQSWQNYMLQLMMQDFQMNVLQVLENPFDERVAAQIPTVHYEFPNGYHQDFGSE 305
            :..: |||: :::||.|||...::||||.:||||.::|:||:||||:||||||.||||:.|:|:|
  Rat   252 WKKKEKLPQ-VSKSWHNYMCNEVIQDFQASVLQVSDSPYDEQVAAQMPTVHYEMPNGYNTDYGAE 315

  Fly   306 RFKIAESLFD---------NAMLGAGQLASTSVGMCDADVRLSLFGSVVVTGGNTLLQGFPERLN 361
            |.:|.|.|||         |.|||.|.:.:||:||||.|:|..|:|||:|||||||||||.:|||
  Rat   316 RLRIPEGLFDPSNVKGLSGNTMLGVGHVVTTSIGMCDIDIRPGLYGSVIVTGGNTLLQGFTDRLN 380

  Fly   362 RDLQLRAPSNTRLKMISANGSVERRFGAWIGGSILASIGTFQQMWISSQEYEEAGKSQVERKCP 425
            |:|..:.|.:.|||:|::|.::||:|..|||||||||:|||||||||.|||||.||..||||||
  Rat   381 RELSQKTPPSMRLKLIASNSTMERKFSPWIGGSILASLGTFQQMWISKQEYEEGGKQCVERKCP 444

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Bap55	NP_611209.1	Actin	13..425	CDD:394979	233/440 (53%)
Actl6b	XP_006249182.1	Actin	11..444	CDD:394979	233/440 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	482	1.000	Domainoid score	I391
eggNOG	1	0.900	-	-		E1_COG5277
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	493	1.000	Inparanoid score	I1346
OMA	1	1.010	-	-		QHG55702
OrthoDB	1	1.010	-	-		D300517at33208
OrthoFinder	1	1.000	-	-		FOG0001878
OrthoInspector	1	1.000	-	-		otm45439
orthoMCL	1	0.900	-	-		OOG6_102754
Panther	1	1.100	-	-	LDO	PTHR11937
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1579
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.840