DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Bap55 and arp42

DIOPT Version :9

Sequence 1:	NP_611209.1	Gene:	Bap55 / 36956	FlyBaseID:	FBgn0025716	Length:	425	Species:	Drosophila melanogaster
Sequence 2:	NP_594546.2	Gene:	arp42 / 2541496	PomBaseID:	SPAC23D3.09	Length:	424	Species:	Schizosaccharomyces pombe

Alignment Length:	442	Identity:	147/442 - (33%)
Similarity:	235/442 - (53%)	Gaps:	48/442 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 DEIGALVFDPGHHSLRVGYAQEDSPKAEIPSVVGIGAAPETNLDPETKTDNNATPNNADQRKFYV 75
            :||.:||.|||....|.|||.|:||...:||..|:              .::.|..|    |:.|
pombe     2 EEIPSLVIDPGSCWTRFGYAGEESPMTILPSYYGV--------------RSDVTGRN----KYVV 48

  Fly    76 DTNYVTVPRSNMEVQTYMKDGMIDNWDLFEKVIDYAYANVIQSEPEYHPVLFSEASWNVRNNREK 140
            |...:..|...|||:....:|:|.:|:......:......:|..|..:.::.:|.|||.::.|::
pombe    49 DELQIHAPIPGMEVKNGKSNGIIQDWESTLYTWERGLKEKLQVNPTEYAMMITEPSWNPQSVRQQ 113

  Fly   141 LTELMFEKYNVPAFFLVKNAVLAAFSSGRATALVVDSGATHTSAVPVHEGYVLSQAVVKSPLGGD 205
            :.|..||:.:||||:|.|.||..||::.::|||:||.|:.:.|..||.:|.::.:.:.|..|.||
pombe   114 IMEAAFEQLHVPAFYLTKQAVCVAFANSKSTALIVDIGSDNASVTPVVDGLIIRKGIFKQSLAGD 178

  Fly   206 FLSRQCRQHLEKHGIDLSPVYKIASKDVVKERD----NGRFTLRK----LP--ENLTQSWQNYML 260
            ||:....|......|:..|.|:||.|.|..::.    ||.....|    .|  ::||.|::.:..
pombe   179 FLNANIEQLFNTMNIEFPPHYRIARKSVAIQQSGNMANGSADAVKPAVLYPPIQDLTSSYEIFQK 243

  Fly   261 QLMMQDFQMNVLQVLENPFDERVAAQIPTVHYEFPNGYHQDFGSERFKIAESLFDNAMLGAGQLA 325
            :.::::::.:||.||:.||||..|:......:|||:|....||.|||:|:|.|| |....|.:.|
pombe   244 RRVIEEWKESVLDVLDTPFDEAKASSRNPKPFEFPDGVTHKFGQERFRISEILF-NPSFSASRSA 307

  Fly   326 ST-----SVGM----------CDADVRLSLFGSVVVTGGNTLLQGFPERLNRDLQLRAPSNTRLK 375
            .|     |||:          ||:::|..|..::|||||.:|:.|..|||..::| |..:.:|:.
pombe   308 ETTPPQGSVGLHELVYQSILACDSELRSPLLNNIVVTGGTSLIPGLSERLQAEVQ-RLATGSRIN 371

  Fly   376 MISANGSVERRFGAWIGGSILASIGTFQQMWISSQEYEEAGKSQ---VERKC 424
            :.:|..:.......|.|||||||:..||.:|:|.|||:|.|..:   ||::|
pombe   372 VHTAETASATSNAVWFGGSILASLDNFQHLWVSKQEYDEVGVDRALFVEKRC 423

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Bap55	NP_611209.1	Actin	13..425	CDD:394979	146/440 (33%)
arp42	NP_594546.2	COG5277	1..421	CDD:227602	145/438 (33%)
arp42	NP_594546.2	Actin	4..424	CDD:278451	146/440 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	236	1.000	Domainoid score	I477
eggNOG	1	0.900	-	-		E1_COG5277
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	235	1.000	Inparanoid score	I836
OMA	1	1.010	-	-		QHG55702
OrthoFinder	1	1.000	-	-		FOG0001878
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_102754
Panther	1	1.100	-	-	LDO	PTHR11937
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1579
TreeFam	1	0.960	-	-
	10	9.830