DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Bap55 and Actl7b

DIOPT Version :9

Sequence 1:	NP_611209.1	Gene:	Bap55 / 36956	FlyBaseID:	FBgn0025716	Length:	425	Species:	Drosophila melanogaster
Sequence 2:	NP_079547.2	Gene:	Actl7b / 11471	MGIID:	1343053	Length:	418	Species:	Mus musculus

Alignment Length:	439	Identity:	125/439 - (28%)
Similarity:	198/439 - (45%)	Gaps:	96/439 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 EIGALVFDPGHHSLRVGYAQEDSPKAEIPSVVGIGAAPETNLDPETKTDNNATPNNADQRKFYVD 76
            :|.|||.|.|....:.|||.|..|...|.|.||..:|...                ||....:.:
Mouse    50 KIKALVIDLGSQYCKCGYAGEPRPTYFISSTVGKRSAEMA----------------ADAGDNFKE 98

  Fly    77 TNYVTVPRSNMEVQ----TYMKDGMIDNWDLFEKVIDYAYANVIQSEPEYHPVLFSEASWNVRNN 137
            | ||.....|||..    ..:|.|::.:||..:.:.:|.:...::..||.|.||.|:...:..:|
Mouse    99 T-YVGHELLNMEASLKLVNPLKHGVVVDWDCIQNIWEYIFHTAMKIMPEEHAVLVSDPPLSPTSN 162

  Fly   138 REKLTELMFEKYNVPAFFLVKNAVLAAFSSGRATALVVDSGATHTSAVPVHEGYVLSQAVVKSPL 202
            |||..||:||.:.:||..:...|:|:.:|.|:.:.|||:||...:..||:.||.:|...    |.
Mouse   163 REKYAELLFETFGIPAMHVTSQALLSIYSYGKTSGLVVESGHGVSHVVPISEGDLLPGL----PS 223

  Fly   203 GGDFLSRQCRQHLEKHGIDLSPVYKIASKDVVKERDNGRFTLRKLPENLTQSWQNYMLQLMMQ-- 265
            ..|:.           |.||:                                 ||::||:.:
Mouse   224 RVDYA-----------GCDLT---------------------------------NYLMQLLNEAG 244

  Fly   266 -DFQMNVLQVLEN-----------PFDERVAAQIPTVH--YEFPNGYHQDFGSERFKIAESLFDN 316
             .|..:.|.::|:           | :|.::..:..:|  ||.|:|.....|.|||:.:|.||..
Mouse   245 HKFSDDHLHIIEHIKKKCCYAALLP-EEEMSLGLDELHVDYELPDGKIITIGQERFRCSEMLFKP 308

  Fly   317 AMLGAGQ-----LASTSVGMCD-ADVRLSLFGSVVVTGGNTLLQGFPERLNRDLQLRAPSNTRLK 375
            :::|..|     |.:|.:..|. ...:..:..:|::.||.|:|.|||||..|:|.|..|.::.
Mouse   309 SLVGCTQPGLPELTATCLARCQGTGFKEEMAANVLLCGGCTMLDGFPERFQRELSLLCPGDSP-- 371

  Fly   376 MISANGSVERRFGAWIGGSILASIGTFQQMWISSQEYEEAGKSQVERKC 424
              :...:.||:...|.|||||||:..|||:|:|.:|:||.|.:.:..||
Mouse   372 --TVAAAPERKTSVWTGGSILASLQAFQQLWVSKEEFEERGCAAIYSKC 418

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Bap55	NP_611209.1	Actin	13..425	CDD:394979	125/438 (29%)
Actl7b	NP_079547.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..42
		ACTIN	52..418	CDD:214592	122/435 (28%)
		NBD_sugar-kinase_HSP70_actin	53..418	CDD:302596	122/434 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5277
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900