DRSC/TRiP Functional Genomics Resources

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Protein Alignment Bap55 and POTEB3

DIOPT Version :9

Sequence 1:NP_611209.1 Gene:Bap55 / 36956 FlyBaseID:FBgn0025716 Length:425 Species:Drosophila melanogaster
Sequence 2:NP_997238.2 Gene:POTEB3 / 102724631 HGNCID:51240 Length:581 Species:Homo sapiens


Alignment Length:378 Identity:71/378 - (18%)
Similarity:122/378 - (32%) Gaps:121/378 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly    10 GDEIGALVFDPGHHSLRVGYAQEDSPK-------AEIPSVVGIGAAPETNLDPETKTDNNATPNN 67
            ||...:...:|.:|..|     ||..|       .::|....|....:|:::...|....|.   
Human   121 GDYDDSAFMEPRYHVRR-----EDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKQKRTAL--- 177

  Fly    68 ADQRKFYVDTNYVTVPRSNMEVQTYMKD-----GMIDN---WDLFEKV-----------IDYAYA 113
                       ::.....|.||...:.|     .::||   ..|.:.|           :::...
Human   178 -----------HLASANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDECVLMLLEHGAD 231

  Fly   114 NVIQSE---PEYHPVLFSEASWNVR-----------NNREKLTELMF----EKYNVPAFFLVKNA 160
            ..||.|   ...|..:::|.....:           .|:..||.|:.    :|..|..|.:.|.|
Human   232 GNIQDEYGNTALHYAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQQVVKFLIKKKA 296

  Fly   161 VLAAFSSGRATALV------------------VDSGATHTSAVPVHEGYVLSQAVVKSPLGGDFL 207
            .|.|......|||:                  ||..:...|.....|..|.|...|...|..|:.
Human   297 NLNALDRYGRTALILAVCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSDYK 361

  Fly   208 SRQCRQHLEKHGIDLSPVYKIASKDVVKERDNGRFTLRKLPENLTQSWQNYMLQLMMQDFQMNVL 272
            .:|              :.||:|::...|:|                     |:|..:: :...|
Human   362 EKQ--------------MLKISSENSNPEQD---------------------LKLTSEE-ESQRL 390

  Fly   273 QVLENPFDERVAAQIPTVHYEFPNGYHQDF---GSERFKIAESLFDNAMLGAG 322
            :|.||...|:: :|.|.::.:......::.   ||....:.|:|.:.|..|.|
Human   391 KVSENSQPEKM-SQEPEINKDCDREVEEEIKKHGSNPVGLPENLTNGASAGNG 442

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Bap55NP_611209.1 Actin 13..425 CDD:394979 69/375 (18%)
POTEB3NP_997238.2 Ank_4 143..193 CDD:290365 8/63 (13%)
ANK 167..292 CDD:238125 22/138 (16%)
ANK 1. /evidence=ECO:0000255 172..201 5/42 (12%)
ANK repeat 174..203 CDD:293786 5/42 (12%)
Ank_2 177..269 CDD:289560 13/105 (12%)
ANK repeat 205..236 CDD:293786 3/30 (10%)
ANK 2. /evidence=ECO:0000255 205..234 2/28 (7%)
ANK 233..357 CDD:238125 26/123 (21%)
ANK repeat 238..269 CDD:293786 2/30 (7%)
ANK 3. /evidence=ECO:0000255 238..267 2/28 (7%)
Ank_2 243..335 CDD:289560 18/91 (20%)
ANK repeat 271..302 CDD:293786 10/30 (33%)
ANK 4. /evidence=ECO:0000255 271..300 9/28 (32%)
ANK repeat 304..335 CDD:293786 5/30 (17%)
ANK 5. /evidence=ECO:0000255 304..333 5/28 (18%)
ANK 6. /evidence=ECO:0000255 337..366 8/42 (19%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 369..494 19/97 (20%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5277
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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