DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Bap55 and LOC100288966

DIOPT Version :9

Sequence 1:	NP_611209.1	Gene:	Bap55 / 36956	FlyBaseID:	FBgn0025716	Length:	425	Species:	Drosophila melanogaster
Sequence 2:	NP_001244291.1	Gene:	LOC100288966 / 100288966	-ID:	-	Length:	584	Species:	Homo sapiens

Alignment Length:	211	Identity:	44/211 - (20%)
Similarity:	73/211 - (34%)	Gaps:	62/211 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   137 NREKLTELMF----EKYNVPAFFLVKNAVLAAFSSGRATALV------------------VDSGA 179
            |:..||.|:.    :|..|..|.:.|.|.|........|||:                  ||..:
Human   269 NKCGLTPLLLGVHEQKQQVVKFLIKKKANLNVLDRYGRTALILAVCCGSASIVNLLLEQNVDVSS 333

  Fly   180 THTSAVPVHEGYVLSQAVVKSPLGGDFLSRQCRQHLEKHGIDLSPVYKIASKDVVKERDNGRFTL 244
            ...|.....|..|.|...|...|..|:..:|              :.||:|::...|:|
Human   334 QDLSGQTAREYAVSSHHHVICELLSDYKEKQ--------------MLKISSENSNPEQD------ 378

  Fly   245 RKLPENLTQSWQNYMLQLMMQDFQMNVLQVLENPFDERVAAQIPTVHYEFPNGYHQDF---GSER 306
                           |:|..:: :...|:|.||...|:: :|.|.::.:......::.   ||..
Human   379 ---------------LKLTSEE-ESQRLKVSENSQPEKM-SQEPEINKDCDREVEEEIKKHGSNP 426

  Fly   307 FKIAESLFDNAMLGAG 322
            ..:.|:|.:.|..|.|
Human   427 VGLPENLTNGASAGNG 442

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Bap55	NP_611209.1	Actin	13..425	CDD:394979	44/211 (21%)
LOC100288966	NP_001244291.1	Ank_4	143..193	CDD:290365
		ANK	167..292	CDD:238125	7/22 (32%)
		ANK repeat	174..203	CDD:293786
		Ank_2	177..269	CDD:289560	44/211 (21%)
		ANK repeat	205..236	CDD:293786
		ANK	233..357	CDD:238125	20/87 (23%)
		ANK repeat	238..269	CDD:293786	44/211 (21%)
		Ank_2	243..335	CDD:289560	15/65 (23%)
		ANK repeat	271..302	CDD:293786	9/30 (30%)
		ANK repeat	304..335	CDD:293786	5/30 (17%)
		SH3_and_anchor	<440..556	CDD:275056	2/3 (67%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5277
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900