Protein Alignment Mtap and PNP

DIOPT Version :10

• Sequence 1: NP_001261049.1
• Gene: Mtap / 36955
• FlyBaseID: FBgn0034215
• Length: 360
• Species: Drosophila melanogaster
• Sequence 2: NP_000261.2
• Gene: PNP / 4860
• HGNCID: 7892
• Length: 289
• Species: Homo sapiens
• Alignment Length: 277
• Identity: 72/277 - (25%)
• Similarity: 122/277 - (44%)
• Gaps: 63/277 - (22%)

  Fly    17 KIGIIGGSGLDD-PDILEQRQERVVETPYGE---------PSDA--LIEGEINGVQCVLLARHGR 69
            ::.||.||||.. .|.|.|.|  :.:  |||         |..|  |:.|.:||..||::.....
Human    26 QVAIICGSGLGGLTDKLTQAQ--IFD--YGEIPNFPRSTVPGHAGRLVFGFLNGRACVMMQGRFH 86

  Fly    70 KHDIMPS-NVNYRANIWALRDVGCTHLIVSTACGSLREEIKPGNLVVPHDFIDRTTKRLQTFYDG 133
            .::..|. .|.:...::.|  :|...|:|:.|.|.|..:.:.|::::..|.|:     |..|
Human    87 MYEGYPLWKVTFPVRVFHL--LGVDTLVVTNAAGGLNPKFEVGDIMLIRDHIN-----LPGF--- 141

  Fly   134 KAQSP-RGVCHLP-------MFPAFSERTRNILLQAA----------KELEIPAHDKATIVTIEG 180
            ..|:| ||    |       .|||.|:.....:.|.|          :||:     :.|.|.:.|
Human   142 SGQNPLRG----PNDERFGDRFPAMSDAYDRTMRQRALSTWKQMGEQRELQ-----EGTYVMVAG 197

  Fly   181 PRFSSRSESHMFRQWGGDLINMTTCPEVVLAKEAGLLYGSVAIAT-----DYDCWRMGCEGVNVQ 240
            |.|.:.:|..:.::.|.|.:.|:|.|||::|:..||.....::.|     ||:    ..|..|.:
Human   198 PSFETVAECRVLQKLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVIMDYE----SLEKANHE 258

  Fly   241 DVLRTFAENVIKVKKIL 257
            :||....:...|:::.:
Human   259 EVLAAGKQAAQKLEQFV 275

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mtap	NP_001261049.1	MTAP_SsMTAPII_like_MTIP	18..261	CDD:350161	72/276 (26%)
PNP	NP_000261.2	PNP-EcPNPII_like	8..276	CDD:350160	72/277 (26%)