DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mtap and SPAC16C9.02c

DIOPT Version :9

Sequence 1:	NP_001261049.1	Gene:	Mtap / 36955	FlyBaseID:	FBgn0034215	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	NP_593076.1	Gene:	SPAC16C9.02c / 2542316	PomBaseID:	SPAC16C9.02c	Length:	307	Species:	Schizosaccharomyces pombe

Alignment Length:	262	Identity:	99/262 - (37%)
Similarity:	140/262 - (53%)	Gaps:	20/262 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 PVKIGIIGGSGLDD-P--DILEQRQERVVETPYGEPSDAL-IEGEINGVQCVLLARHGRKHDIMP 75
            |:.:|:|||||..| |  ||:|....   .||:|.|:..: |....:|.....|||||..|...|
pombe     7 PILLGVIGGSGFYDLPGFDIVESVNP---ITPWGYPASPISIARTTSGFLIAFLARHGVGHIYTP 68

  Fly    76 SNVNYRANIWALRDVGCTHLIVSTACGSLREEIKPGNLVVPHDFIDRT-TKRLQTFYDGKAQSPR 139
            :.|..||||.||:.:|...::..:|.|||||:|.|.:.|:|...|||| ..|..||::...
pombe    69 TEVPSRANIAALKSLGVLAIVSFSAVGSLREDIPPEDFVLPTQIIDRTLCARPNTFFESGC---- 129

  Fly   140 GVCHLPMFPAFSERTRNILLQAAKELEIPAH-------DKATIVTIEGPRFSSRSESHMFRQWGG 197
             |.|:.....|.:....||......|:..:.       |..|:|.:|||.||:|:||:::|.||.
pombe   130 -VAHVSFGDPFDQDLYEILSSCGSNLKNGSKLHTKRKGDDLTVVCMEGPAFSTRAESNLYRSWGA 193

  Fly   198 DLINMTTCPEVVLAKEAGLLYGSVAIATDYDCWRMGCEGVNVQDVLRTFAENVIKVKKILVNAVG 262
            .:|||:..||..||:||.:.|..|.:|||||||||..|.|.|:.|:...:.|....|..|:.||.
pombe   194 SIINMSVIPEAKLAREAEIAYQMVCMATDYDCWRMNEEPVTVETVMEHISNNKDNAKIFLLEAVK 258

  Fly   263 RI 264
            ::
pombe   259 KL 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mtap	NP_001261049.1	XapA	12..264	CDD:223084	99/260 (38%)
Mtap	NP_001261049.1	PNP_UDP_1	17..263	CDD:294213	98/257 (38%)
SPAC16C9.02c	NP_593076.1	XapA	6..260	CDD:223084	99/260 (38%)
SPAC16C9.02c	NP_593076.1	MTAP	9..259	CDD:273762	98/257 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	134	1.000	Domainoid score	I1278
eggNOG	1	0.900	-	-		E1_COG0005
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1838
Inparanoid	1	1.050	155	1.000	Inparanoid score	I1278
OMA	1	1.010	-	-		QHG62280
OrthoFinder	1	1.000	-	-		FOG0004468
OrthoInspector	1	1.000	-	-		otm47130
orthoMCL	1	0.900	-	-		OOG6_101599
Panther	1	1.100	-	-	LDO	PTHR42679
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R756
SonicParanoid	1	1.000	-	-		X3167
TreeFam	1	0.960	-	-
	14	13.860