Protein Alignment CG6550 and miaB

DIOPT Version :10

• Sequence 1: NP_611207.1
• Gene: CG6550 / 36954
• FlyBaseID: FBgn0034214
• Length: 552
• Species: Drosophila melanogaster
• Sequence 2: NP_415194.1
• Gene: miaB / 945260
• ECOCYCID: G6364
• Length: 474
• Species: Escherichia coli
• Alignment Length: 494
• Identity: 144/494 - (29%)
• Similarity: 235/494 - (47%)
• Gaps: 54/494 - (10%)

  Fly    70 TQKVFVKTWGCAHNNSDSEYMAGQL-AAYGYRLSG-KEEADLWLLNSCTVKNPSEDTFRNEIESG 132
            |:|:.:|||||..|..||..||..| |.:||:|:. .||||:.|||:|:::..:::...:::...
E. coli     2 TKKLHIKTWGCQMNEYDSSKMADLLDATHGYQLTDVAEEADVLLLNTCSIREKAQEKVFHQLGRW 66

  Fly   133 M----RNGKHVV-VAGCV--PQG---APKSDYLNGLSVIGVQQIDRVVEVVEETLKGHSVQLLQN 187
            .    :|...:: |.|||  .:|   ..::.|::  .:.|.|.:.|:.|::
E. coli    67 KLLKEKNPDLIIGVGGCVASQEGEHIRQRAHYVD--IIFGPQTLHRLPEMI-------------- 115

  Fly   188 KKKVHGRRVAGAPLSLPKVRK-----NPLIE----IISINSGCLNQCTYCKTKHARGDLASYPPE 243
             ..|.|.|.....:|.|::.|     .|..|    .:||..||...||||...:.||:..|.|.:
E. coli   116 -NSVRGDRSPVVDISFPEIEKFDRLPEPRAEGPTAFVSIMEGCNKYCTYCVVPYTRGEEVSRPSD 179

  Fly   244 EVVERARQSFAEGCCEIWLTSEDTGAY-GRDIG---SSLPELLWQLVEVIPEHCMLRVGMTNPPY 304
            :::....|..|:|..|:.|..::..|: |.:..   .|..:|| :||..|.....:|...::|
E. coli   180 DILFEIAQLAAQGVREVNLLGQNVNAWRGENYDGTTGSFADLL-RLVAAIDGIDRIRFTTSHP-- 241

  Fly   305 ILEHLEEVANVLQH-PRVYSFLHVPVQSGSDSVLGEMKREYCRQDFEHVVDFLRERVPGVTIATD 368
             :|..:::..|.:. |.:.||||:|||||||.:|..|.|.:...:::.::..||...|.:.|::|
E. coli   242 -IEFTDDIIEVYRDTPELVSFLHLPVQSGSDRILNLMGRTHTALEYKAIIRKLRAARPDIQISSD 305

  Fly   369 IICGFPTETEDDFEETMTLCAKYRFPSLFINQFFPRPGTPAAKM-DRIPANLVKKRTKRLTDLFY 432
            .|.|||.||.:|||:||.|.|...|...:...|..|||||||.| |.:|....|:|...|.:...
E. coli   306 FIVGFPGETTEDFEKTMKLIADVNFDMSYSFIFSARPGTPAADMVDDVPEEEKKQRLYILQERIN 370

  Fly   433 SYEPYADR--VGEIYTVLVTEVSHDK-LHYVGHNKSYEQVLLPMRDNLLGTRVHVRITSASKFSM 494
            .......|  :|....:||...|... :...|..::...|......:::|..|.|.||.....|:
E. coli   371 QQAMAWSRRMLGTTQRILVEGTSRKSIMELSGRTENNRVVNFEGTPDMIGKFVDVEITDVYPNSL 435

  Fly   495 VGEILDDERDW-TRCAKNQELPNVQVQTRSRERLIQRYF 532
            .|:::..|.:. .|.|:..|  :|..:||....|...|:
E. coli   436 RGKVVRTEDEMGLRVAETPE--SVIARTRKENDLGVGYY 472

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6550	NP_611207.1	MiaB-like-B	72..549	CDD:273703	143/492 (29%)
miaB	NP_415194.1	miaB-methiolase	4..440	CDD:273700	134/456 (29%)