DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6550 and AT1G72090

DIOPT Version :9

Sequence 1:	NP_611207.1	Gene:	CG6550 / 36954	FlyBaseID:	FBgn0034214	Length:	552	Species:	Drosophila melanogaster
Sequence 2:	NP_565035.1	Gene:	AT1G72090 / 843540	AraportID:	AT1G72090	Length:	601	Species:	Arabidopsis thaliana

Alignment Length:	531	Identity:	264/531 - (49%)
Similarity:	350/531 - (65%)	Gaps:	48/531 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 VDDIEDL---------------ISADDVKPRERYENKKTVTVRAKKRSQIRLESQEEEEKPKPTI 62
            ::|||||               ::|..:.|:.. ::|:.    :.|..||...:::....|
plant     1 MEDIEDLLAGGVGGAPPGFRLPLNAVGINPKTN-KSKRI----SSKPDQITASNRDSLAPP---- 56

  Fly    63 HESVIPGTQKVFVKTWGCAHNNSDSEYMAGQLAAYGYRLSG-KEEADLWLLNSCTVKNPSEDTFR 126
             ...|||||.:::||:||:||.||||||||||:|:||.|:. .|||||||:|:||||:||:....
plant    57 -SMKIPGTQTIYIKTFGCSHNQSDSEYMAGQLSAFGYALTEVPEEADLWLINTCTVKSPSQSAMS 120

  Fly   127 NEIESGMRNGKHVVVAGCVPQGAPKSDYLNGLSVIGVQQIDRVVEVVEETLKGHSVQLLQNKKKV 191
            ..|..|....|.:|:|||||||:.....|.|:||:||||||||||:||||||||.|:||..|..
plant   121 TLITRGRSGKKPLVIAGCVPQGSRDLKELEGVSVVGVQQIDRVVEIVEETLKGHEVRLLTRKTL- 184

  Fly   192 HGRRVAGAPLSLPKVRKNPLIEIISINSGCLNQCTYCKTKHARGDLASYPPEEVVERARQSFAEG 256
                   ..|.|||||:|..|||:.||.|||..|||||||||||.|.||..:.:|||.|...:||
plant   185 -------PALDLPKVRRNNFIEILPINVGCLGACTYCKTKHARGHLGSYTVDSLVERVRTVISEG 242

  Fly   257 CCEIWLTSEDTGAYGRDIGSSLPELLWQLVEVIP--EHCMLRVGMTNPPYILEHLEEVANVLQHP 319
            ..||||:||||||||||||.:||.||..:|:.:|  :..|||:||||||:|||||:|:|.||:||
plant   243 VKEIWLSSEDTGAYGRDIGVNLPILLNAIVKELPSDQSTMLRIGMTNPPFILEHLKEIAAVLRHP 307

  Fly   320 RVYSFLHVPVQSGSDSVLGEMKREYCRQDFEHVVDFLRERVPGVTIATDIICGFPTETEDDFEET 384
            .||:||||||||||||||..|.|||...:|..|||.|.|.|||:.||||||||||.||::||.:|
plant   308 CVYTFLHVPVQSGSDSVLTAMNREYTASEFRTVVDTLTELVPGMQIATDIICGFPGETDEDFSQT 372

  Fly   385 MTLCAKYRFPSLFINQFFPRPGTPAAKMDRIPANLVKKRTKRLTDLFYSYEPYADRVGEIYTVLV 449
            :.|...|:||.:.|:||:||||||||||.::.:.:||:|::.||.:|.::.||.........:.:
plant   373 VELIKDYKFPQVHISQFYPRPGTPAAKMKKVQSKIVKQRSRELTSVFEAFAPYTGMECREERIWI 437

  Fly   450 TEVSHDKLHYVGHNKSYEQVLLPMRDNLLGTRVHVRITSASKFSMVGEILDDERDWTRCAKNQEL 514
            |||:.|.:|.|||.|.|.|||:...:::|||....||||..::|:.||:::     |..:.|:|
plant   438 TEVATDGIHLVGHTKGYVQVLVTGPESMLGTSAMARITSVGRWSVFGEVIE-----TFSSANRE- 496

  Fly   515 PNVQVQTRSRE 525
                  |:|||
plant   497 ------TKSRE 501

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6550	NP_611207.1	MiaB-like-B	72..549	CDD:273703	247/457 (54%)
		UPF0004	72..151	CDD:279287	45/79 (57%)
		Radical_SAM	215..413	CDD:100105	127/199 (64%)
AT1G72090	NP_565035.1	UPF0004	65..156	CDD:279287	49/90 (54%)
		MiaB-like-B	66..487	CDD:273703	240/428 (56%)
		Radical_SAM	201..406	CDD:100105	128/204 (63%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	223	1.000	Domainoid score	I704
eggNOG	1	0.900	-	-		E1_COG0621
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9830
Inparanoid	1	1.050	491	1.000	Inparanoid score	I327
OMA	1	1.010	-	-		QHG62224
OrthoDB	1	1.010	-	-		D835984at2759
OrthoFinder	1	1.000	-	-		FOG0005706
OrthoInspector	1	1.000	-	-		oto2926
orthoMCL	1	0.900	-	-		OOG6_101475
Panther	1	1.100	-	-	LDO	PTHR11918
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4103
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840