DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG6550 and Cdk5rap1

DIOPT Version :9

Sequence 1:NP_611207.1 Gene:CG6550 / 36954 FlyBaseID:FBgn0034214 Length:552 Species:Drosophila melanogaster
Sequence 2:NP_663773.1 Gene:Cdk5rap1 / 252827 RGDID:708387 Length:586 Species:Rattus norvegicus


Alignment Length:525 Identity:138/525 - (26%)
Similarity:228/525 - (43%) Gaps:104/525 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly    51 SQEEEEKPKPTIHESVIPGTQ-KVFVKTWGCAHNNSDSEYMAGQLAAYGY-RLSGKEEADLWLLN 113
            |..|.|.|.|.:....:.|.| ||:::|:||..|.:|:|.....|...|| |.|..:|||:.||.
  Rat    76 SSPEVEDPPPYLSGDELLGRQRKVYLETYGCQMNVNDTEIAWSILQKSGYLRTSNLQEADVILLV 140

  Fly   114 SCTVKNPSEDTFRNEIES---------GMRNGKHVVVAGCVPQGAPKSDYLNGLSVIGV------ 163
            :|:::..:|.|..|.:..         ..|....:.:.||:.:.. |.:.||...::.:      
  Rat   141 TCSIREKAEQTIWNRLHQLKVLKAKRPRSRVPLRIGILGCMAERL-KGEILNREKMVDLLAGPDA 204

  Fly   164 -QQIDRVVEVVEETLKGHSVQLLQNKKKVHGRRVAGAPLSLPK-------VRKNP--LIEIISIN 218
             :.:.|::.|||.                 |::.|...|||.:       |:.:|  ....:||.
  Rat   205 YRDLPRLLAVVES-----------------GQQAANVLLSLDETYADIMPVQTSPSATSAFVSIM 252

  Fly   219 SGCLNQCTYCKTKHARGDLASYPPEEVVERARQSFAEGCCEIWLTSEDTGAYGRD--------IG 275
            .||.|.|:||.....||...|.|...:::..|:...:|..|:.|..::..:: ||        .|
  Rat   253 RGCDNMCSYCIVPFTRGRERSRPVASILDEVRKLSEQGLKEVTLLGQNVNSF-RDNSEVQFSSTG 316

  Fly   276 SS------------------LPELLWQLVEVIPEHCMLRVGMTN------PPYILEHLEEVANVL 316
            |:                  ...||.|:..:.||   :|:..|:      |..:|:.:.|..|:.
  Rat   317 SANLSRGFTTNYKPKQGGLRFSHLLDQVSRIDPE---MRIRFTSPHPKDFPDEVLQLIRERHNIC 378

  Fly   317 QHPRVYSFLHVPVQSGSDSVLGEMKREYCRQDFEHVVDFLRERVPGVTIATDIICGFPTETEDDF 381
            :.      :|:|.||||..||..|:|.|.|:.:..:|..:||.:|||.:::|.|.||..|||||.
  Rat   379 KQ------IHLPAQSGSSRVLEAMRRGYSREAYVALVHHIREAIPGVGLSSDFITGFCGETEDDH 437

  Fly   382 EETMTLCAKYRFPSLFINQFFPRPGTPA--AKMDRIPANLVKKRTKRLTDLF--YSYEPYADRVG 442
            .:|::|..:.::.:.|:..:..|..|.|  ...|.:|..:..:|.:.|..:|  .:.:..|..||
  Rat   438 LQTVSLLREVQYNTGFLFAYSMRQKTRAYHRLKDDVPEEVKLRRLEELITVFREEASKVNATSVG 502

  Fly   443 EIYTVLVTEVS-HDKLHYVGHNKSYEQVLLP------MRDNLL------GTRVHVRITSASKFSM 494
            ....|||...| .......|.|.:..:|:.|      :.|..|      |..|.|:|.|||..::
  Rat   503 CTQLVLVEGFSKRSTTDLCGRNDANLKVIFPDAEVEDITDPGLKVRAQPGDYVLVKIISASSQTL 567

  Fly   495 VGEIL 499
            .|.||
  Rat   568 KGHIL 572

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG6550NP_611207.1 MiaB-like-B 72..549 CDD:273703 131/503 (26%)
UPF0004 72..151 CDD:279287 25/88 (28%)
Radical_SAM 215..413 CDD:100105 64/231 (28%)
Cdk5rap1NP_663773.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 68..90 5/13 (38%)
PRK14329 85..571 CDD:237676 132/513 (26%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0621
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D407532at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
32.820

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