DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6550 and Y92H12BL.1

DIOPT Version :9

Sequence 1:	NP_611207.1	Gene:	CG6550 / 36954	FlyBaseID:	FBgn0034214	Length:	552	Species:	Drosophila melanogaster
Sequence 2:	NP_740783.2	Gene:	Y92H12BL.1 / 190786	WormBaseID:	WBGene00022363	Length:	425	Species:	Caenorhabditis elegans

Alignment Length:	368	Identity:	211/368 - (57%)
Similarity:	280/368 - (76%)	Gaps:	12/368 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   141 VAGCVPQGAPKSDYLNGLSVIGVQQIDRVVEVVEETLKGHSVQLLQNKKKVHGRRVAGAPLSLPK 205
            :||||.|.||...:|..:|::||:||||:||||.|||||:.|:||.       |....|.|||||
Worm     1 MAGCVSQAAPSEPWLQNVSIVGVKQIDRIVEVVGETLKGNKVRLLT-------RNRPDAVLSLPK 58

  Fly   206 VRKNPLIEIISINSGCLNQCTYCKTKHARGDLASYPPEEVVERARQSF-AEGCCEIWLTSEDTGA 269
            :|||.|||::||::||||.|||||||.|||||.|||..::||:||.:| .||..|:||||||.||
Worm    59 MRKNELIEVLSISTGCLNNCTYCKTKMARGDLVSYPLADLVEQARAAFHDEGVKELWLTSEDLGA 123

  Fly   270 YGRDIGSSLPELLWQLVEVIPEHCMLRVGMTNPPYILEHLEEVANVLQHPRVYSFLHVPVQSGSD 334
            :|||||..||:||.:||:|||:..|:|:|||||||||:||||:|.:|.||:||:|||:||||.||
Worm   124 WGRDIGLVLPDLLRELVKVIPDGSMMRLGMTNPPYILDHLEEIAEILNHPKVYAFLHIPVQSASD 188

  Fly   335 SVLGEMKREYCRQDFEHVVDFLRERVPGVTIATDIICGFPTETEDDFEETMTLCAKYRFPSLFIN 399
            :||.:|||||.|:.||.:.|::...||.:.||||:|..|||||.:||||:|.|..||:|||||||
Worm   189 AVLNDMKREYSRRHFEQIADYMIANVPNIYIATDMILAFPTETLEDFEESMELVRKYKFPSLFIN 253

  Fly   400 QFFPRPGTPAAKMDRIPANLVKKRTKRLTDLFYSYEPYAD-RVGEIYTVLVTEVSHDKLHYVGHN 463
            |::||.|||||::.:|.....:|||..:::||.||..|.| |:||::.||||||:.||||.||||
Worm   254 QYYPRSGTPAARLKKIDTVEARKRTAAMSELFRSYTRYTDERIGELHRVLVTEVAADKLHGVGHN 318

  Fly   464 KSYEQVLLPMRDNLLGTRVHVRITSASKFSMVGE---ILDDER 503
            |||||:|:|:....:|..:.||:|:.:||||:.:   |.:|::
Worm   319 KSYEQILVPLEYCKMGEWIEVRVTAVTKFSMISKPASIQEDQQ 361

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6550	NP_611207.1	MiaB-like-B	72..549	CDD:273703	211/368 (57%)
		UPF0004	72..151	CDD:279287	6/9 (67%)
		Radical_SAM	215..413	CDD:100105	127/198 (64%)
Y92H12BL.1	NP_740783.2	Elp3	67..268	CDD:214792	127/200 (64%)
Y92H12BL.1	NP_740783.2	Radical_SAM	68..273	CDD:100105	128/204 (63%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160166954
Domainoid	1	1.000	233	1.000	Domainoid score	I1352
eggNOG	1	0.900	-	-		E1_COG0621
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9830
Inparanoid	1	1.050	425	1.000	Inparanoid score	I981
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG62224
OrthoDB	1	1.010	-	-		D407532at33208
OrthoFinder	1	1.000	-	-		FOG0005706
OrthoInspector	1	1.000	-	-		oto18882
orthoMCL	1	0.900	-	-		OOG6_101475
Panther	1	1.100	-	-	LDO	PTHR11918
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2445
SonicParanoid	1	1.000	-	-		X4103
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.800