DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment l(2)k01209 and DAS2

DIOPT Version :9

Sequence 1:	NP_725672.2	Gene:	l(2)k01209 / 36953	FlyBaseID:	FBgn0022029	Length:	626	Species:	Drosophila melanogaster
Sequence 2:	NP_010303.3	Gene:	DAS2 / 851583	SGDID:	S000002427	Length:	232	Species:	Saccharomyces cerevisiae

Alignment Length:	217	Identity:	50/217 - (23%)
Similarity:	95/217 - (43%)	Gaps:	38/217 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   188 VIGICGGSASGKTTVA-------EKIIESLDVPWVTLLSM-DCFYKILNEKQHEQALINEYNFDH 244
            ||.|.||.|:|...:|       :.:..|:::..:.|.:| :...|..|.        |:|:||
Yeast    12 VISIGGGHATGVGAIALDLQNTFKSLYNSINIRVINLDNMIEGNIKSYNN--------NDYDFD- 67

  Fly   245 PDAFDIELLLDVLTKLKEGRKVEVPVYNFVTHGRESQTKTMYGANVIIFEGILTFHSPEVLKLLD 309
                      ::|..:.|...| ....:.:.|..|..      .::||..|....:...:.::..
Yeast    68 ----------NILNLVYEKHAV-TSQNDMIQHDYEDP------IDLIIVCGCYALYDKRINEISQ 115

  Fly   310 MKIFVDTDPDIRLARRLRRDISQRGRDLKGVLKQYLNMVKPSYCNYIAPTMAHADIIVPRGGDN- 373
            :|:|:|:|.|.||...:::........|..::.:|::.::|....||.||...||:|:|...:|
Yeast   116 LKVFLDSDADKRLISLIKKKNVGSNEQLAQLITEYMDHLRPEMQQYIEPTRTFADLIIPSTNENL 180

  Fly   374 --KVAIHLIVQHVH-TQLQLRG 392
              .|.:..||:.:. |:.|:.|
Yeast   181 GRAVLVDGIVKAIEDTKSQIEG 202

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
l(2)k01209	NP_725672.2	Udk	186..397	CDD:223645	50/217 (23%)
		UMPK	188..387	CDD:238981	47/210 (22%)
		UPRTase	417..620	CDD:291353
DAS2	NP_010303.3	Udk	8..209	CDD:223645	50/217 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0572
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810