DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment l(2)k01209 and UKL3

DIOPT Version :9

Sequence 1:	NP_725672.2	Gene:	l(2)k01209 / 36953	FlyBaseID:	FBgn0022029	Length:	626	Species:	Drosophila melanogaster
Sequence 2:	NP_001323275.1	Gene:	UKL3 / 842031	AraportID:	AT1G55810	Length:	488	Species:	Arabidopsis thaliana

Alignment Length:	466	Identity:	208/466 - (44%)
Similarity:	295/466 - (63%)	Gaps:	45/466 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   185 EPFVIGICGGSASGKTTVAEKIIESLDVPWVTLLSMDCFYKILNEKQHEQALINEYNFDHPDAFD 249
            :|||||:.||:|||||||.:.|::.|......:::.|.||..:||.  |...:::||||||||||
plant    43 QPFVIGVAGGAASGKTTVCDMIMQQLHDQRAVVVNQDSFYHNVNEV--ELVRVHDYNFDHPDAFD 105

  Fly   250 IELLLDVLTKLKEGRKVEVPVYNFVTH-GRESQTKTMYGANVIIFEGILTFHSPEVLKLLDMKIF 313
            .|.||..:.||::|:.|::|.|:|.:: ......:.:..::|||.||||.||.|.|..|::||||
plant   106 TEQLLSSMEKLRKGQAVDIPNYDFKSYKNNVFPPRRVNPSDVIILEGILIFHDPRVRDLMNMKIF 170

  Fly   314 VDTDPDIRLARRLRRDISQRGRDLKGVLKQYLNMVKPSYCNYIAPTMAHADIIVPRGGDNKVAIH 378
            ||.|.|:|||||::||..::|||:..||.||...|||::.::|.||..:||||:||||||.|||.
plant   171 VDADADVRLARRIKRDTVEKGRDIATVLDQYSKFVKPAFEDFILPTKKYADIIIPRGGDNHVAID 235

  Fly   379 LIVQHVHTQLQLRGFKLRETLANSYKDQPMPHSLHLLHPTPQIKGLHTFIRCRNTSRDEFIFYSK 443
            |||||:||:|.      :..|...|.      :|:::..|.||:|:||.||...|::.:|||||.
plant   236 LIVQHIHTKLG------QHDLCKIYP------NLYVIQSTFQIRGMHTLIRDSKTTKHDFIFYSD 288

  Fly   444 RLIRLVIEYALSLFPFKKTTVETPQGVLYEGKRMESRKICGVSILRAGETMEQAVCDVCKDIRIG 508
            ||||||:|:.|...||.:..|.||.|.:|.|... .:|:||||::|:||:||.|:...||.|:||
plant   289 RLIRLVVEHGLGHLPFTEKQVVTPTGSVYSGVDF-CKKLCGVSVIRSGESMENALRACCKGIKIG 352

  Fly   509 KILIQ------------------------TNLKTGEPELYYLRLPKDIKDYKVILMDATVATGAA 549
            ||||.                        ||   |..:|.|.:||.||.:..|:|:|..:.||.:
plant   353 KILIHREGDNGQQVCVLSLLITSPNYLLTTN---GTHQLIYEKLPSDISERHVLLLDPILGTGNS 414

  Fly   550 AMMAIRVLLDHDVPEDNIILASLLMAEIGVHSIAYAFPKVKIVTSALDPEINSKFYVIPGIGNFG 614
            |:.|||:|:...|||.|||..:|:.|..||:.:...||::|||||.::..:|.:|.|:||:|.||
plant   415 AVQAIRLLISKGVPESNIIFLNLISAPEGVNVVCKKFPRIKIVTSEIELGLNDEFRVVPGMGEFG 479

  Fly   615 DRYFGTEPSDE 625
            ||||||:  ||
plant   480 DRYFGTD--DE 488

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
l(2)k01209	NP_725672.2	Udk	186..397	CDD:223645	103/211 (49%)
		UMPK	188..387	CDD:238981	99/199 (50%)
		UPRTase	417..620	CDD:291353	98/226 (43%)
UKL3	NP_001323275.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	201	1.000	Domainoid score	I867
eggNOG	1	0.900	-	-		E1_COG0572
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	401	1.000	Inparanoid score	I464
OMA	1	1.010	-	-		QHG55607
OrthoDB	1	1.010	-	-		D929897at2759
OrthoFinder	1	1.000	-	-		FOG0001406
OrthoInspector	1	1.000	-	-		otm3153
orthoMCL	1	0.900	-	-		OOG6_100147
Panther	1	1.100	-	-	O	PTHR10285
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X779
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.840