DRSC/TRiP Functional Genomics Resources

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Protein Alignment l(2)k01209 and UCK2

DIOPT Version :10

Sequence 1:NP_725672.2 Gene:l(2)k01209 / 36953 FlyBaseID:FBgn0022029 Length:626 Species:Drosophila melanogaster
Sequence 2:NP_036606.2 Gene:UCK2 / 7371 HGNCID:12562 Length:261 Species:Homo sapiens


Alignment Length:228 Identity:115/228 - (50%)
Similarity:162/228 - (71%) Gaps:10/228 - (4%)


- Green bases have known domain annotations that are detailed below.


  Fly   185 EPFVIGICGGSASGKTTVAEKIIESL---DVPW----VTLLSMDCFYKILNEKQHEQALINEYNF 242
            |||:||:.||:||||::|..||::.|   :|.:    |.:||.|.||::|..:|..:||..::||
Human    19 EPFLIGVSGGTASGKSSVCAKIVQLLGQNEVDYRQKQVVILSQDSFYRVLTSEQKAKALKGQFNF 83

  Fly   243 DHPDAFDIELLLDVLTKLKEGRKVEVPVYNFVTHGRESQTKTMYGANVIIFEGILTFHSPEVLKL 307
            |||||||.||:|..|.::.||:.|::|||:||:|.|:.:|.|:|.|:|::|||||.|:|.||..|
Human    84 DHPDAFDNELILKTLKEITEGKTVQIPVYDFVSHSRKEETVTVYPADVVLFEGILAFYSQEVRDL 148

  Fly   308 LDMKIFVDTDPDIRLARRLRRDISQRGRDLKGVLKQYLNMVKPSYCNYIAPTMAHADIIVPRGGD 372
            ..||:|||||.|.||:||:.||||:|||||:.:|.||:..|||::..:..||..:||:|:|||.|
Human   149 FQMKLFVDTDADTRLSRRVLRDISERGRDLEQILSQYITFVKPAFEEFCLPTKKYADVIIPRGAD 213

  Fly   373 NKVAIHLIVQHVHTQLQLRGFKLRET--LANSY 403
            |.|||:|||||:...|. .|...|:|  ..|.|
Human   214 NLVAINLIVQHIQDILN-GGPSKRQTNGCLNGY 245

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
l(2)k01209NP_725672.2 UMPK 188..387 CDD:238981 106/205 (52%)
UPRTase 417..620 CDD:434124
UCK2NP_036606.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..24 3/4 (75%)
UMPK 22..228 CDD:238981 106/205 (52%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 236..261 4/10 (40%)
Blue background indicates that the domain is not in the aligned region.

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