DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment l(2)k01209 and nmrk2

DIOPT Version :9

Sequence 1:	NP_725672.2	Gene:	l(2)k01209 / 36953	FlyBaseID:	FBgn0022029	Length:	626	Species:	Drosophila melanogaster
Sequence 2:	NP_001008079.1	Gene:	nmrk2 / 493441	XenbaseID:	XB-GENE-5806910	Length:	203	Species:	Xenopus tropicalis

Alignment Length:	217	Identity:	52/217 - (23%)
Similarity:	88/217 - (40%)	Gaps:	34/217 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   188 VIGICGGSASGKTTVAEKIIESLDVPWVTLLSMDCFYKILNEKQHEQALINEYNFDHPDAFDIEL 252
            ::||.|.:..||||:..|:|.:|  |...::..|.|:| ..:|...|....:|  |...|.|:|.
Frog     4 IVGIGGVTNGGKTTLTNKLINAL--PNCCVVHQDDFFK-PQDKIEVQDGFKQY--DVITALDMEA 63

  Fly   253 LLDVLTK-LKEGRKVEVP--VYNFVTHGRESQTKTMYGANVIIFEGILTFHSPEVLKLLDMKIFV 314
            ::..:.. .|:..|.|..  :.|.:.......|:.....:|:|.||.|.:....::.|.....|:
Frog    64 MMSTIDGWRKDPAKFERSHGINNALDSETPQDTEENESLHVLIVEGFLLYTYKPLIDLFTKCYFL 128

  Fly   315 DTDPDIRLARRLRRDISQRGRDLKGVLKQYLNMVKPSYCNYIAPTMAHADIIVPRGGDNKVAIHL 379
            ....|....||..|:.:.  .|..|:...:   |.|.|       :.|.:|:        ..:::
Frog   129 SVPYDECKRRRSSRNYTV--PDPPGLFDGH---VWPMY-------IKHKNIM--------EELNV 173

  Fly   380 IVQHVHTQLQLRGFKLRETLAN 401
            .|:      ||.|...||.|.|
Frog   174 NVE------QLDGTNTREELFN 189

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
l(2)k01209	NP_725672.2	Udk	186..397	CDD:223645	48/211 (23%)
		UMPK	188..387	CDD:238981	45/201 (22%)
		UPRTase	417..620	CDD:291353
nmrk2	NP_001008079.1	NRK1	4..170	CDD:238982	44/190 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910