DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment l(2)k01209 and ctnnb1

DIOPT Version :10

Sequence 1:NP_725672.2 Gene:l(2)k01209 / 36953 FlyBaseID:FBgn0022029 Length:626 Species:Drosophila melanogaster
Sequence 2:XP_005157888.1 Gene:ctnnb1 / 30265 ZFINID:ZDB-GENE-980526-362 Length:789 Species:Danio rerio


Alignment Length:510 Identity:103/510 - (20%)
Similarity:166/510 - (32%) Gaps:165/510 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly   235 ALINEYNFDHPDAFDIELLLDVLTKLKEGRKVEVPVYNFVTHGRESQTKTMYGANVIIFEGILTF 299
            ||:|:.|...     :.:..|.|..|..|.: |..:....:.|.::....|   ....:|.:| :
Zfish   283 ALLNKTNVKF-----LAITTDCLQILAYGNQ-ESKLIILASGGPQALVNIM---RTYTYEKLL-W 337

  Fly   300 HSPEVLKLLDM-----KIFVD-----------TDPDIRLARR----LRR--------------DI 330
            .:..|||:|.:     ...|:           |||..||.:.    ||.              |:
Zfish   338 TTSRVLKVLSVCSSNKPAIVEAGGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQTSLAEVDV 402

  Fly   331 SQRGRDLKGVLKQYL-----NMVKPS-------YCNYIAPTMAHADI--------IVPRGGD--- 372
            .:....|.|.|.|.|     |:|..:       .||.....|....:        .|.|.||   
Zfish   403 QEGMEGLLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDRED 467

  Fly   373 -NKVAI----HLIVQHVHTQLQLRGFKLRETLANSYKDQPMPHSLHLLHPT---PQIKGLHTFIR 429
             .:.||    ||..:|...::.....:|...|         |..:.||||.   |.||.....||
Zfish   468 ITEPAICALRHLTSRHQDAEMAQNAVRLHYGL---------PVVVKLLHPPSHWPLIKATVGLIR 523

  Fly   430 ----C---RNTSRDEFIFYSKRLIRLVIEYALSLFPFKKTTVETPQGVLYEGKRME--------- 478
                |   ....|::...  .||::|::.....  ..::|::...|....||.|||         
Zfish   524 NLALCPANHAPLREQGAI--PRLVQLLVRAHQD--TQRRTSMGGTQQQFVEGVRMEEIVEGCTGA 584

  Fly   479 ----SRKICGVSILRAGETMEQAV------------------CDVCKDIRIGKILIQTNLKTGEP 521
                :|.|....::|...|:...|                  |::.:|....:.:..........
Zfish   585 LHILARDIHNRIVIRGLNTIPLFVQLLYSPIENIQRVAAGVLCELAQDKEAAEAIEAEGATAPLT 649

  Fly   522 ELYYLRLPKDIKDYKVILMDATVATGAAAMMAIRVLLDHDVPED-----NIILASLLM------- 574
            ||.:.|             :..|||.|||::   ..:..|.|:|     ::.|.|.|.       
Zfish   650 ELLHSR-------------NEGVATYAAAVL---FRMSEDKPQDYKKRLSVELTSSLFRTEPMTW 698

  Fly   575 ---AEIGVHSIAYAFPKVKIVTSALDPEINSKFYVIPGIGNFGDRYFGTEPSDEY 626
               .::|:...|...|   :.....||...| |:    .|.:|....|.:|..|:
Zfish   699 NETGDLGLDIGAQGEP---LGYRQDDPSYRS-FH----SGGYGQDAMGMDPMMEH 745

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
l(2)k01209NP_725672.2 UMPK 188..387 CDD:238981 45/213 (21%)
UPRTase 417..620 CDD:434124 49/258 (19%)
ctnnb1XP_005157888.1 CTNNAbd_CTNNB1 77..150 CDD:439241
SRP1 141..>455 CDD:227396 36/181 (20%)
armadillo repeat 152..177 CDD:293788
armadillo repeat 187..220 CDD:293788
armadillo repeat 229..261 CDD:293788
ARM 229..261 CDD:214547
armadillo repeat 269..305 CDD:293788 7/26 (27%)
armadillo repeat 311..346 CDD:293788 7/38 (18%)
ARM 349..389 CDD:214547 8/39 (21%)
armadillo repeat 353..389 CDD:293788 8/35 (23%)
armadillo repeat 410..435 CDD:293788 6/24 (25%)
Arm 439..481 CDD:425727 9/41 (22%)
armadillo repeat 443..481 CDD:293788 9/37 (24%)
armadillo repeat 490..525 CDD:293788 12/43 (28%)
armadillo repeat 532..590 CDD:293788 11/61 (18%)
Arm 593..630 CDD:425727 4/36 (11%)
armadillo repeat 595..629 CDD:293788 4/33 (12%)
armadillo repeat 637..670 CDD:293788 9/48 (19%)
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.