DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment l(2)k01209 and bar-1

DIOPT Version :9

Sequence 1:	NP_725672.2	Gene:	l(2)k01209 / 36953	FlyBaseID:	FBgn0022029	Length:	626	Species:	Drosophila melanogaster
Sequence 2:	NP_509206.1	Gene:	bar-1 / 180982	WormBaseID:	WBGene00000238	Length:	811	Species:	Caenorhabditis elegans

Alignment Length:	425	Identity:	86/425 - (20%)
Similarity:	144/425 - (33%)	Gaps:	142/425 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   243 DHPDAFDIELLLDVLTKLKEGRKVEVPVY------NFVTHGRESQTKTMYGAN-VIIFEGILTFH 300
            |.|.....:|||..|.:|...|...:.:|      |.|.:.|.:: :.|.|.| |:|....||..
Worm   370 DVPSKIKEDLLLKSLLELVNSRNTTIRLYSAQIMSNLVANNRHNK-EFMCGNNGVVILVRALTIA 433

  Fly   301 SPEVLKLLD-----------------------------MKIFVDTDPDIRLARRLRRDISQRGRD 336
            :.|:..|.|                             ::.||..||    |..|.:.::.|...
Worm   434 TKEMGDLRDKEAQQMEDYIESLICTLRHLCVGHPMSDKVQAFVFRDP----ALFLHKLLTMRPVL 494

  Fly   337 LKGVLKQYLNMVKPSYCNYIAPTMAHADIIVP----RGGDN---KVAIHLI---VQHVHTQLQLR 391
            ||..|...|.:|.           .|| ::.|    |.||.   :..||::   ...::.|..:.
Worm   495 LKHTLSLLLKVVS-----------QHA-LLAPFRSCRIGDKGFVEQLIHILRVACTQLNVQESIE 547

  Fly   392 GFKLRETLANSYKDQPMPHSLHLLHPTPQIKGLHTFIRCRNTSRDE-------FIFYSKRLIRLV 449
            |.::::                ::|...||        .|..:||:       |...:....|:.
Worm   548 GVRVKD----------------IIHLCIQI--------LRWITRDQDILNEVVFFLQTPENSRMG 588

  Fly   450 IEYALSLFPFKKTTVETPQGVLYEGKRMESRKICGVSILRAGETMEQAVCDVCKDIRIGKIL--I 512
            ..:.|.:|..:|..||            |:.|...::::......||....:.:|..:.|:|  :
Worm   589 DGHTLPIFVLQKANVE------------ENTKSSALALIYNLMHHEQMANVLDRDDVLVKMLQNV 641

  Fly   513 QTNLKTGEPELYYLRLPKDIKDYKVILMDATVATGAAAMM-AIRVLLDHDVPEDNIILASLLMAE 576
            |...:| .|||                  |::|.....|| ..|....:.:|..|    |.|.::
Worm   642 QMQSQT-HPEL------------------ASLANNILKMMYEKREKTRNTLPRYN----SYLESQ 683

  Fly   577 IGVHSIAYAFPKVKIVTSALDPEINSKFYVIPGIG 611
            .|..|          :|:.....:||...|..|.|
Worm   684 FGHMS----------MTTPRSEALNSSGEVCEGAG 708

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
l(2)k01209	NP_725672.2	Udk	186..397	CDD:223645	44/199 (22%)
		UMPK	188..387	CDD:238981	42/189 (22%)
		UPRTase	417..620	CDD:291353	41/205 (20%)
bar-1	NP_509206.1	armadillo repeat	120..145	CDD:293788
		armadillo repeat	155..195	CDD:293788
		armadillo repeat	201..240	CDD:293788
		armadillo repeat	294..331	CDD:293788
		ARM	296..408	CDD:237987	10/37 (27%)
		armadillo repeat	337..368	CDD:293788
		Extensin_2	739..796	CDD:252669
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0572
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900