DRSC/TRiP Functional Genomics Resources

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Protein Alignment l(2)k01209 and UPRT

DIOPT Version :9

Sequence 1:NP_725672.2 Gene:l(2)k01209 / 36953 FlyBaseID:FBgn0022029 Length:626 Species:Drosophila melanogaster
Sequence 2:NP_659489.1 Gene:UPRT / 139596 HGNCID:28334 Length:309 Species:Homo sapiens


Alignment Length:288 Identity:105/288 - (36%)
Similarity:152/288 - (52%) Gaps:41/288 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly   364 DIIVPRGGDNKVA---IHLIVQHVHTQLQLR-------GFKLRET------LANSYKDQPMPHS- 411
            |:|:...|.|:.:   :.|:..:.|:.|...       |..|...      .::|| |.|..:| 
Human    33 DLILDHAGGNRASRAKVILLTGYAHSSLPAELDSGACGGSSLNSEGNSGSGDSSSY-DAPAGNSF 96

  Fly   412 -------------LHLLHPTPQIKGLHTFIRCRNTSRDEFIFYSKRLIRLVIEYALSLFPFKKTT 463
                         |.||....||:.|.|.||.:..||.:|:|.:.||||||:|..|:..|:|:..
Human    97 LEDCELSRQIGAQLKLLPMNDQIRELQTIIRDKTASRGDFMFSADRLIRLVVEEGLNQLPYKECM 161

  Fly   464 VETPQGVLYEGKRMESRKICGVSILRAGETMEQAVCDVCKDIRIGKILIQTNLKTGEPELYYLRL 528
            |.||.|..|||.:.|... |||||:|:||.|||.:.|.|:.|||||||||::.:|...::||.:.
Human   162 VTTPTGYKYEGVKFEKGN-CGVSIMRSGEAMEQGLRDCCRSIRIGKILIQSDEETQRAKVYYAKF 225

  Fly   529 PKDIKDYKVILMDATVATGAAAMMAIRVLLDHDVPEDNIILASLLMAEIGVHSIAYAFPKVKIVT 593
            |.||...||:||...::||...:.|::||::|.|....|||.||.....|..||...||::.|:|
Human   226 PPDIYRRKVLLMYPILSTGNTVIEAVKVLIEHGVQPSVIILLSLFSTPHGAKSIIQEFPEITILT 290

  Fly   594 SALDPEINSKFYVIPGIGNFGDRYFGTE 621
            :.:.|       |.|  .:||.:||||:
Human   291 TEVHP-------VAP--THFGQKYFGTD 309

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
l(2)k01209NP_725672.2 Udk 186..397 CDD:223645 9/42 (21%)
UMPK 188..387 CDD:238981 6/25 (24%)
UPRTase 417..620 CDD:291353 86/202 (43%)
UPRTNP_659489.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..38 2/4 (50%)
UPRTase 118..308 CDD:317125 86/199 (43%)
5-phospho-alpha-D-ribose 1-diphosphate binding. /evidence=ECO:0000250|UniProtKB:Q26998 238..246 2/7 (29%)
Uracil binding. /evidence=ECO:0000250|UniProtKB:Q26998 299..301 0/1 (0%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D929897at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 1 0.900 - - OOG6_100147
Panther 1 1.100 - - O PTHR10285
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R1606
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
54.950

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