Protein Alignment l(2)k01209 and UPRT

DIOPT Version :10

• Sequence 1: NP_725672.2
• Gene: l(2)k01209 / 36953
• FlyBaseID: FBgn0022029
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: NP_659489.1
• Gene: UPRT / 139596
• HGNCID: 28334
• Length: 309
• Species: Homo sapiens
• Alignment Length: 288
• Identity: 105/288 - (36%)
• Similarity: 152/288 - (52%)
• Gaps: 41/288 - (14%)

  Fly   364 DIIVPRGGDNKVA---IHLIVQHVHTQLQLR-------GFKLRET------LANSYKDQPMPHS- 411
            |:|:...|.|:.:   :.|:..:.|:.|...       |..|...      .::|| |.|..:|
Human    33 DLILDHAGGNRASRAKVILLTGYAHSSLPAELDSGACGGSSLNSEGNSGSGDSSSY-DAPAGNSF 96

  Fly   412 -------------LHLLHPTPQIKGLHTFIRCRNTSRDEFIFYSKRLIRLVIEYALSLFPFKKTT 463
                         |.||....||:.|.|.||.:..||.:|:|.:.||||||:|..|:..|:|:..
Human    97 LEDCELSRQIGAQLKLLPMNDQIRELQTIIRDKTASRGDFMFSADRLIRLVVEEGLNQLPYKECM 161

  Fly   464 VETPQGVLYEGKRMESRKICGVSILRAGETMEQAVCDVCKDIRIGKILIQTNLKTGEPELYYLRL 528
            |.||.|..|||.:.|... |||||:|:||.|||.:.|.|:.|||||||||::.:|...::||.:.
Human   162 VTTPTGYKYEGVKFEKGN-CGVSIMRSGEAMEQGLRDCCRSIRIGKILIQSDEETQRAKVYYAKF 225

  Fly   529 PKDIKDYKVILMDATVATGAAAMMAIRVLLDHDVPEDNIILASLLMAEIGVHSIAYAFPKVKIVT 593
            |.||...||:||...::||...:.|::||::|.|....|||.||.....|..||...||::.|:|
Human   226 PPDIYRRKVLLMYPILSTGNTVIEAVKVLIEHGVQPSVIILLSLFSTPHGAKSIIQEFPEITILT 290

  Fly   594 SALDPEINSKFYVIPGIGNFGDRYFGTE 621
            :.:.|       |.|  .:||.:||||:
Human   291 TEVHP-------VAP--THFGQKYFGTD 309

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
l(2)k01209	NP_725672.2	UMPK	188..387	CDD:238981	6/25 (24%)
		UPRTase	417..620	CDD:434124	86/202 (43%)
UPRT	NP_659489.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..38		2/4 (50%)
		UPRTase	118..308	CDD:434124	86/199 (43%)