DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment l(2)k01209 and uprt

DIOPT Version :9

Sequence 1:	NP_725672.2	Gene:	l(2)k01209 / 36953	FlyBaseID:	FBgn0022029	Length:	626	Species:	Drosophila melanogaster
Sequence 2:	XP_002931835.1	Gene:	uprt / 100487820	XenbaseID:	XB-GENE-998574	Length:	257	Species:	Xenopus tropicalis

Alignment Length:	232	Identity:	97/232 - (41%)
Similarity:	137/232 - (59%)	Gaps:	13/232 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   390 LRGFKLRETLANSYKDQPMPHSLHLLHPTPQIKGLHTFIRCRNTSRDEFIFYSKRLIRLVIEYAL 454
            |.|..|:|...:..:..|   .|.||....||:.|.|.||.|:|||.:|:|.:.||||||:|..|
Frog    39 LDGLPLQELPKDQQQVGP---QLKLLPMNDQIRELQTIIRDRSTSRGDFVFSADRLIRLVVEEGL 100

  Fly   455 SLFPFKKTTVETPQGVLYEGKRMESRKICGVSILRAGETMEQAVCDVCKDIRIGKILIQTNLKTG 519
            :..|:.:.||.||.|..|:|.:.|... |||||:|:||.|||.:.|.|:.|||||||||::.:|.
Frog   101 NQLPYTECTVTTPTGYKYDGVKFEKGN-CGVSIMRSGEAMEQGLRDCCRSIRIGKILIQSDEETQ 164

  Fly   520 EPELYYLRLPKDIKDYKVILMDATVATGAAAMMAIRVLLDHDVPEDNIILASLLMAEIGVHSIAY 584
            :.::||.:.|.||...||:||...::||...:.|::||::|.|....|||.||.....|..||..
Frog   165 KAKVYYAKFPPDIYRRKVLLMYPILSTGNTVIEAVKVLIEHGVQPACIILLSLFSTPHGAISIIQ 229

  Fly   585 AFPKVKIVTSALDPEINSKFYVIPGIGNFGDRYFGTE 621
            .||.:.|:|:.:.|       |.|  .:||.:||||:
Frog   230 EFPDITILTTEVHP-------VAP--THFGQKYFGTD 257

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
l(2)k01209	NP_725672.2	Udk	186..397	CDD:223645	3/6 (50%)
		UMPK	188..387	CDD:238981
		UPRTase	417..620	CDD:291353	87/202 (43%)
uprt	XP_002931835.1	UPRTase	66..256	CDD:373220	87/199 (44%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D929897at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10285
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1606
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.140