DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment l(2)k01209 and uck2a

DIOPT Version :9

Sequence 1:	NP_725672.2	Gene:	l(2)k01209 / 36953	FlyBaseID:	FBgn0022029	Length:	626	Species:	Drosophila melanogaster
Sequence 2:	NP_001164538.1	Gene:	uck2a / 100005763	ZFINID:	ZDB-GENE-030131-7158	Length:	261	Species:	Danio rerio

Alignment Length:	207	Identity:	109/207 - (52%)
Similarity:	152/207 - (73%)	Gaps:	7/207 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   185 EPFVIGICGGSASGKTTVAEKIIESL-------DVPWVTLLSMDCFYKILNEKQHEQALINEYNF 242
            :||:||:.||:||||::|..||:|.|       ....|.:||.|.||::|..:|..:||..::||
Zfish    21 QPFLIGVAGGTASGKSSVCGKIMELLGQNKIDHHQRQVAILSQDSFYRVLTPEQKAKALKGQFNF 85

  Fly   243 DHPDAFDIELLLDVLTKLKEGRKVEVPVYNFVTHGRESQTKTMYGANVIIFEGILTFHSPEVLKL 307
            |||||||.||::..|.::.|||.|::|||:||||.|:.:|.|:|.|:|::|||||.|:|.|:..|
Zfish    86 DHPDAFDNELIVKTLCEIMEGRTVQIPVYDFVTHSRKEETVTVYPADVVLFEGILMFYSQEIRDL 150

  Fly   308 LDMKIFVDTDPDIRLARRLRRDISQRGRDLKGVLKQYLNMVKPSYCNYIAPTMAHADIIVPRGGD 372
            ..||:|||||.|.||:||:.||||:|||||:.||.||:..|||::..:..||..:||:|:|||.|
Zfish   151 FQMKLFVDTDADTRLSRRVLRDISERGRDLEQVLNQYITFVKPAFEEFCLPTKKYADVIIPRGAD 215

  Fly   373 NKVAIHLIVQHV 384
            |.|||:|||||:
Zfish   216 NLVAINLIVQHI 227

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
l(2)k01209	NP_725672.2	Udk	186..397	CDD:223645	109/206 (53%)
		UMPK	188..387	CDD:238981	107/204 (52%)
		UPRTase	417..620	CDD:291353
uck2a	NP_001164538.1	Udk	21..232	CDD:223645	109/207 (53%)
uck2a	NP_001164538.1	UMPK	24..229	CDD:238981	107/204 (52%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0572
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D509086at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100147
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1606
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.750