DRSC/TRiP Functional Genomics Resources

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Protein Alignment cnk and ipcef1

DIOPT Version :10

Sequence 1:NP_725671.1 Gene:cnk / 36952 FlyBaseID:FBgn0286070 Length:1557 Species:Drosophila melanogaster
Sequence 2:XP_073789335.1 Gene:ipcef1 / 767791 ZFINID:ZDB-GENE-060929-172 Length:407 Species:Danio rerio


Alignment Length:446 Identity:109/446 - (24%)
Similarity:164/446 - (36%) Gaps:134/446 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly   707 RRNTNLKLLGTGDIQGHLYRRKKNHRGVT--YWARIYFVMLDTILYGFRSKQSTSASLVIFLPGF 769
            ||..::|.||.||.||.||:||:: :|:.  .|.:.:||:....||.:.|..:..|...|.|..|
Zfish    64 RRRVSVKDLGQGDCQGWLYKRKES-KGLLGWKWKKFWFVLKKCSLYWYTSDMAEKAEGYINLRDF 127

  Fly   770 TVSLAKEVHSKPHAFKVYHT-AKSFYFAAESLDALNQWVDFLRQASLKVPPSTGSKGGGDAKDLY 833
            |:..|.|. .|..|.|..|. ..:.||||||:..:|:|:..|.|||.:..|:..:.|     :.|
Zfish   128 TIEQATEC-KKKFAMKASHLHVLTLYFAAESMKDMNKWLAKLTQASNEPEPTDSTNG-----ECY 186

  Fly   834 SENDSSGEECDALVIQNLSTPSPQGNKESMSMSMTLSGGTPPSSAPIKHERGYLDSFRKFTNTFK 898
            || :|..|:.:.:.::.:...:|.          :|.|..||                      .
Zfish   187 SE-ESDDEDDEEMCVEYMDQLTPG----------SLHGCLPP----------------------P 218

  Fly   899 SSAAKPSSDIPVPTEQYRSYRKVPGGSFGIQIGANTPGYHDPAMPPTQIPPLVGPKLSRSSSRSS 963
            .|::.|..|                                       :.|||          ||
Zfish   219 RSSSSPFQD---------------------------------------VIPLV----------SS 234

  Fly   964 VVSGTESAVSLSASILGPPASPAPTPTPTATPTSLQHQSSEESPSQSQSQ-----SPSSKS---- 1019
            |.|.||                    |.:|...|.|..||||.|.....|     .|:|..    
Zfish   235 VCSRTE--------------------TQSADSESWQEISSEEDPILKIQQCKGNDGPASDEMEML 279

  Fly  1020 --SLKKAPFNFLHASNPNLVEFDFHTSKTLLPKMSVGNTLDHGHNIQGF-VTLKDLMLRKQEEEA 1081
              .||:|..:...|..| ..:.||.:|  .:.:....|..|..|.|:.. .|||   .::.:.:|
Zfish   280 YLHLKEASLSPTGALQP-FTKRDFRSS--FIRRCKDENINDKLHLIRALNSTLK---AKEADLQA 338

  Fly  1082 QEMYNNRVHLGVEKHKHARTESTASQQ---SAMSSSVTKPL-EKLPKIQSVSLPKT 1133
            .|...:...|...|::..|..:....|   ....|.|.||: :..|:.||:..|.|
Zfish   339 IEQVLSEPSLNGSKYRQWRDANVLLLQEIGEKHKSDVEKPMVQTRPQRQSLYGPNT 394

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
cnkNP_725671.1 SAM_CNK1,2,3-suppressor 6..74 CDD:188910
CRIC_ras_sig 82..165 CDD:463138
PDZ_CNK1_2_3-like 203..283 CDD:467230
PH_CNK_insect-like 720..810 CDD:270135 32/92 (35%)
ipcef1XP_073789335.1 None
Blue background indicates that the domain is not in the aligned region.

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