DRSC/TRiP Functional Genomics Resources

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Protein Alignment cnk and Ipcef1

DIOPT Version :10

Sequence 1:NP_725671.1 Gene:cnk / 36952 FlyBaseID:FBgn0286070 Length:1557 Species:Drosophila melanogaster
Sequence 2:XP_038937175.2 Gene:Ipcef1 / 361474 RGDID:735159 Length:497 Species:Rattus norvegicus


Alignment Length:447 Identity:112/447 - (25%)
Similarity:176/447 - (39%) Gaps:94/447 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly   707 RRNTNLKLLGTGDIQGHLYRRKKNHRGV---TYWARIYFVMLDTILYGFRSKQSTSASLVIFLPG 768
            ||..:.|.||..|.||.||  ||..:|.   ..|.:.:.|:..:.||.:.::.:..|...:.||.
  Rat    89 RRRISCKDLGHADCQGWLY--KKKEKGTFLSNKWKKFWVVLKGSSLYWYGNQLAEKADGFVNLPD 151

  Fly   769 FTVSLAKEVHSKPHAFKVYH-TAKSFYFAAESLDALNQWVDFLRQASLKVPPSTGSKGGGDAKDL 832
            |||..|.|. .|.:|||:.| ..|:||||||:|..:|.|::.|..|......:|..      ::.
  Rat   152 FTVERASEC-KKKNAFKINHPQIKTFYFAAENLQEMNMWLNKLGFAVTHKESTTKD------EEC 209

  Fly   833 YSENDSSGEECDALVIQNLSTPSPQGNKESMSMSMTLSGGTPPSSAPIKHERGYLDSFRKFTNTF 897
            |||::....|      ..:..|.|   ..:.:.|..::.....||:|.:.|...  ||....||.
  Rat   210 YSESEQEDPE------TAVEAPPP---PSASATSSPVAARRASSSSPKRRETSC--SFSSLENTV 263

  Fly   898 KSSAAKPSSDIPVPTEQYRSYRKVPGGSFGIQIGANTPGYHDPAMP---PTQIPPLVGPKLS--R 957
            |:.:...||.    :::.:|:         :.|..::|...|...|   ..|:..|...:.|  |
  Rat   264 KAPSRFSSSG----SKERQSW---------LDIVNSSPATEDVGHPLSFAVQVHTLASSEASSCR 315

  Fly   958 SSSRSSVVSGTESAVSLSA---SILGPPASPAPTPTPTATPTSLQH---QSSEESPSQSQSQS-- 1014
            .|..||....:....|||:   |.|.........|...:.......   :|||:...:...:|  
  Rat   316 VSENSSTTPESGCLNSLSSDDTSSLNNSQDHLTVPDRASGSRMTDRDEIKSSEDDEMEKLYKSLE 380

  Fly  1015 -----------PSSKSSLKKAPFNFL-HASNPNLVEFDFHTSKTLLPKMSVGNTLD-HGHNIQGF 1066
                       ||:|..|:|   :|: ...||::.| ..|..:||      .:||. ..|::...
  Rat   381 QASLSPLGDRRPSTKKELRK---SFVKRCKNPSINE-KLHKIRTL------NSTLKCKEHDLAMI 435

  Fly  1067 VTLKD---LMLRKQEE-------EAQEMYNNRVHLGVEKH---------KHARTEST 1104
            ..|.|   |..||..|       ..|::|..:.|  |..|         ||:..|.:
  Rat   436 NQLLDDPKLTARKYREWKVMNTLLIQDIYQQQSH--VVTHCCVAISSQTKHSSMEGS 490

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
cnkNP_725671.1 SAM_CNK1,2,3-suppressor 6..74 CDD:188910
CRIC_ras_sig 82..165 CDD:463138
PDZ_CNK1_2_3-like 203..283 CDD:467230
PH_CNK_insect-like 720..810 CDD:270135 34/93 (37%)
Ipcef1XP_038937175.2 None
Blue background indicates that the domain is not in the aligned region.

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