| Sequence 1: | NP_001286524.1 | Gene: | cnk / 36952 | FlyBaseID: | FBgn0286070 | Length: | 1557 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001124171.1 | Gene: | IPCEF1 / 26034 | HGNCID: | 21204 | Length: | 438 | Species: | Homo sapiens |
| Alignment Length: | 473 | Identity: | 116/473 - (24%) |
|---|---|---|---|
| Similarity: | 195/473 - (41%) | Gaps: | 76/473 - (16%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 684 SELHTPSKSRTLTLKKKHSLMAKRRNTNLKLLGTGDIQGHLYRRKKNHRGVT-YWARIYFVMLDT 747
Fly 748 ILYGFRSKQSTSASLVIFLPGFTVSLAKEVHSKPHAFKVYH-TAKSFYFAAESLDALNQWVDFLR 811
Fly 812 QASLKVPPSTGSKGGGDAKDLYSENDSSGEECDALVIQNLSTPSPQGNKESMSMSMTLSGGTPPS 876
Fly 877 SAPIKHERGYLDSFRKFTNTFKSSAAKPSSDIPVPTEQYRSYRKVPGG--SFGIQIGANTP---G 936
Fly 937 YHDPAMPPTQIPPLVGPKLSRSSSRSSVVSGTESAVSLSASILGPPASPAPTPTPTATPTSLQHQ 1001
Fly 1002 SSEESPSQSQSQS---------PSSKSSLKKAPFNFL-HASNPNLVEFDFHTSKTLLPKMSVGNT 1056
Fly 1057 LD-HGHNIQGFVTLKD---LMLRKQEE-------EAQEMYNNRVHLGVEKHKHARTESTASQQSA 1110
Fly 1111 MSSSVTKPLEKLPKIQSV 1128 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| cnk | NP_001286524.1 | SAM_CNK1,2,3-suppressor | 6..74 | CDD:188910 | |
| SAM | 7..74 | CDD:197735 | |||
| CRIC_ras_sig | 82..165 | CDD:287501 | |||
| PDZ_signaling | 206..283 | CDD:238492 | |||
| PH | 720..814 | CDD:278594 | 32/95 (34%) | ||
| PH_CNK_insect-like | 720..810 | CDD:270135 | 31/91 (34%) | ||
| IPCEF1 | NP_001124171.1 | PH_CNK_mammalian-like | 31..144 | CDD:269962 | 39/113 (35%) |
| PH | 45..140 | CDD:278594 | 32/95 (34%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 144..226 | 19/94 (20%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 274..308 | 8/33 (24%) | |||
| CRAC domain | 316..321 | 0/4 (0%) | |||
| CRAC domain | 340..349 | 3/11 (27%) | |||
| Required for interaction with CYTH2. /evidence=ECO:0000269|PubMed:22085542 | 390..438 | 11/60 (18%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 407..438 | 7/43 (16%) | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C165158472 | |
| Domainoid | 1 | 1.000 | 59 | 1.000 | Domainoid score | I10664 |
| eggNOG | 1 | 0.900 | - | - | E1_KOG1738 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D1121556at2759 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0001221 | |
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 7 | 6.710 | |||||