DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosalpha5 and PRE2

DIOPT Version :9

Sequence 1:	NP_477202.2	Gene:	Prosalpha5 / 36951	FlyBaseID:	FBgn0016697	Length:	244	Species:	Drosophila melanogaster
Sequence 2:	NP_015428.1	Gene:	PRE2 / 856218	SGDID:	S000006307	Length:	287	Species:	Saccharomyces cerevisiae

Alignment Length:	228	Identity:	52/228 - (22%)
Similarity:	105/228 - (46%)	Gaps:	27/228 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 IKL--GSTAIGICTPEGVVLAVEKRITSPLMVPS-TVEKIVEVDKHIGCATSGLMADARTLIERA 92
            ||:  |:|.:......|:::||:.|.|:...|.| ||:|::|::..:....:|..||.:......
Yeast    70 IKIAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWL 134

  Fly    93 RVECQNHWFVYNERMSIESCAQAVSTLAIQFGDSGDSDGA--AAMSRPFGVAILFAGIEAGQPQL 155
            ..:|:.|.....||:|:.:.::.:|.|..|:..:|.|.|.  ...:|..|            |.:
Yeast   135 GSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEG------------PTI 187

  Fly   156 WHMDPSGTFVRHGAKAIGSGSEGAQQNLQDLFRPDLTLDEAIDISLNT-LKQVMEEKLNSTNVEV 219
            :::|..||.::.....:|||...|...|...::.||::::|:.:...: |.....:..:..:|.:
Yeast   188 YYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNL 252

  Fly   220 MTMTKEREFY--------MFTK-EEVEQHIKNI 243
            ..:|::...|        :|.| :|.|....|:
Yeast   253 YHVTEDGWIYHGNHDVGELFWKVKEEEGSFNNV 285

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha5	NP_477202.2	PRK03996	8..243	CDD:235192	51/226 (23%)
Prosalpha5	NP_477202.2	proteasome_alpha_type_5	8..222	CDD:239722	45/196 (23%)
PRE2	NP_015428.1	proteasome_beta_type_5	76..264	CDD:239730	44/199 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810