Protein Alignment Prosalpha5 and PRE8

DIOPT Version :10

• Sequence 1: NP_477202.2
• Gene: Prosalpha5 / 36951
• FlyBaseID: FBgn0016697
• Length: 244
• Species: Drosophila melanogaster
• Sequence 2: NP_013618.1
• Gene: PRE8 / 854882
• SGDID: S000004557
• Length: 250
• Species: Saccharomyces cerevisiae
• Alignment Length: 251
• Identity: 79/251 - (31%)
• Similarity: 129/251 - (51%)
• Gaps: 24/251 - (9%)

  Fly     8 YDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGICTPEGVVLAVEKRITSPLMVPSTVEKIVEVDK 72
            |...:.||||.|:|.|::||:.|:|.|.|::||....|||:|.||:.:|||.:..|:.|:..:..
Yeast     5 YSFSLTTFSPSGKLGQIDYALTAVKQGVTSLGIKATNGVVIATEKKSSSPLAMSETLSKVSLLTP 69

  Fly    73 HIGCATSGLMADARTLIERAR-VECQNHWFVYNERMSIESCAQAVSTLAIQFGDSGDSDGAAAMS 136
            .||...||:..|.|.|::::| |...::..:|.|....:.....|:.:..:...||.       .
Yeast    70 DIGAVYSGMGPDYRVLVDKSRKVAHTSYKRIYGEYPPTKLLVSEVAKIMQEATQSGG-------V 127

  Fly   137 RPFGVAILFAG-IEAGQPQLWHMDPSGTFVRHGAKAIGSGSEGAQQNLQDLFRPDLTLDEAIDIS 200
            |||||::|.|| .|.....|:.:||||::....|.|||.||..|:..|:..:..:|.|::||.|:
Yeast   128 RPFGVSLLIAGHDEFNGFSLYQVDPSGSYFPWKATAIGKGSVAAKTFLEKRWNDELELEDAIHIA 192

  Fly   201 LNTLKQVMEEKLNSTNVEVMTMTKER---------------EFYMFTKEEVEQHIK 241
            |.|||:.:|.:.|...:|:..:..|.               .|...|.:|:...::
Yeast   193 LLTLKESVEGEFNGDTIELAIIGDENPDLLGYTGIPTDKGPRFRKLTSQEINDRLE 248

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha5	NP_477202.2	proteasome_alpha_type_5	8..222	CDD:239722	75/215 (35%)
PRE8	NP_013618.1	proteasome_alpha_type_2	5..247	CDD:239719	79/248 (32%)