Protein Alignment Prosalpha5 and PUP1

DIOPT Version :10

• Sequence 1: NP_477202.2
• Gene: Prosalpha5 / 36951
• FlyBaseID: FBgn0016697
• Length: 244
• Species: Drosophila melanogaster
• Sequence 2: NP_014800.3
• Gene: PUP1 / 854328
• SGDID: S000005683
• Length: 261
• Species: Saccharomyces cerevisiae
• Alignment Length: 258
• Identity: 60/258 - (23%)
• Similarity: 108/258 - (41%)
• Gaps: 47/258 - (18%)

  Fly     3 LTRSEYDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGICTPEGVVLAVEKRIT-SPLMVPSTVEK 66
            |:...|.|  |.|..|....|.    :|...|:|.:|:....|||:|.:.|.| .|::......|
Yeast     4 LSFDNYQR--NNFLAENSHTQP----KATSTGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAK 62

  Fly    67 IVEVDKHIGCATSGLMADARTLIERARVECQNHWFVYNERMSIESCAQAVSTLAIQFGDSGDSDG 131
            :..:...|.||.:|..||...:.:......:.|....:....:.|..|.:.....::
Yeast    63 LHRISPKIWCAGAGTAADTEAVTQLIGSNIELHSLYTSREPRVVSALQMLKQHLFKY-------- 119

  Fly   132 AAAMSRPFGVAILFAGIEAGQPQLWHMDPSGTFV----RHGAK------AIGSGSEGAQQNLQDL 186
                ....|..::.||:          ||:|:.:    .||:.      ::||||..|...|:..
Yeast   120 ----QGHIGAYLIVAGV----------DPTGSHLFSIHAHGSTDVGYYLSLGSGSLAAMAVLESH 170

  Fly   187 FRPDLTLDEAIDISLNTLKQVMEEKLNS-TNVE--VMTMTKEREF---YMF--TKEEVEQHIK 241
            ::.|||.:|||.::.:.::..:...|.| :||:  ||.:.|:.|:   |:.  .:||.::..|
Yeast   171 WKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVDVCVMEIGKDAEYLRNYLTPNVREEKQKSYK 233

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha5	NP_477202.2	proteasome_alpha_type_5	8..222	CDD:239722	53/227 (23%)
PUP1	NP_014800.3	proteasome_beta_type_7	30..219	CDD:239732	47/210 (22%)
		Pr_beta_C	222..257	CDD:463597	3/12 (25%)