DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Prosalpha5 and PSMB7

DIOPT Version :9

Sequence 1:	NP_477202.2	Gene:	Prosalpha5 / 36951	FlyBaseID:	FBgn0016697	Length:	244	Species:	Drosophila melanogaster
Sequence 2:	NP_002790.1	Gene:	PSMB7 / 5695	HGNCID:	9544	Length:	277	Species:	Homo sapiens

Alignment Length:	233	Identity:	48/233 - (20%)
Similarity:	94/233 - (40%)	Gaps:	24/233 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 SEYDRGVNTFS----PEGRLFQVEYAIEAIKL------GSTAIGICTPEGVVLAVEKRITSPLMV 60
            |.|...|..||    ....:.:.::|....||      |:|..|:...:|:||..:.|.|..::|
Human     5 SVYAPPVGGFSFDNCRRNAVLEADFAKRGYKLPKVRKTGTTIAGVVYKDGIVLGADTRATEGMVV 69

  Fly    61 -PSTVEKIVEVDKHIGCATSGLMADARTLIERARVECQNHWFVYNERMSIESCAQAVSTLAIQFG 124
             .....||..:..:|.|..:|..||.....:......:.|.........:.:..:.:..:..::
Human    70 ADKNCSKIHFISPNIYCCGAGTAADTDMTTQLISSNLELHSLSTGRLPRVVTANRMLKQMLFRY- 133

  Fly   125 DSGDSDGAAAMSRPFGVAILFAGIEAGQPQLWHMDPSGTFVRHGAKAIGSGSEGAQQNLQDLFRP 189
                       ....|.|::..|::...|.|:.:.|.|:..:.....:||||..|....:|.|||
Human   134 -----------QGYIGAALVLGGVDVTGPHLYSIYPHGSTDKLPYVTMGSGSLAAMAVFEDKFRP 187

  Fly   190 DLTLDEAIDISLNTLKQVMEEKLNS-TNVEVMTMTKER 226
            |:..:||.::....:...:...|.| :|:::..::|.:
Human   188 DMEEEEAKNLVSEAIAAGIFNDLGSGSNIDLCVISKNK 225

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha5	NP_477202.2	PRK03996	8..243	CDD:235192	47/231 (20%)
Prosalpha5	NP_477202.2	proteasome_alpha_type_5	8..222	CDD:239722	46/225 (20%)
PSMB7	NP_002790.1	proteasome_beta_type_7	44..232	CDD:239732	39/194 (20%)
PSMB7	NP_002790.1	Pr_beta_C	236..271	CDD:403609
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810