Protein Alignment Prosalpha5 and PSMB3

DIOPT Version :10

• Sequence 1: NP_477202.2
• Gene: Prosalpha5 / 36951
• FlyBaseID: FBgn0016697
• Length: 244
• Species: Drosophila melanogaster
• Sequence 2: NP_002786.2
• Gene: PSMB3 / 5691
• HGNCID: 9540
• Length: 205
• Species: Homo sapiens
• Alignment Length: 188
• Identity: 35/188 - (18%)
• Similarity: 73/188 - (38%)
• Gaps: 20/188 - (10%)

  Fly    46 VVLAVEKRI-TSPLMVPSTVEKIVEVDKHIGCATSGLMADARTLIERARVECQNHWFVYNERMSI 109
            |.:|.::|. ....||.:..:||..:...:....:||..|.:|:.:|.:.....:......::..
Human    20 VAIAADRRFGIQAQMVTTDFQKIFPMGDRLYIGLAGLATDVQTVAQRLKFRLNLYELKEGRQIKP 84

  Fly   110 ESCAQAVSTLAIQ--FGDSGDSDGAAAMSRPFGVAILFAGIE--AGQPQLWHMDPSG-TFVRHGA 169
            .:....|:.|..:  ||             |:....:.||::  ..:|.:..:|..| ..|....
Human    85 YTLMSMVANLLYEKRFG-------------PYYTEPVIAGLDPKTFKPFICSLDLIGCPMVTDDF 136

  Fly   170 KAIGSGSEGAQQNLQDLFRPDLTLDEAID-ISLNTLKQVMEEKLNSTNVEVMTMTKER 226
            ...|:.:|......:.|:.|::..|...: ||...|..|..:.::...|.|..:.|::
Human   137 VVSGTCAEQMYGMCESLWEPNMDPDHLFETISQAMLNAVDRDAVSGMGVIVHIIEKDK 194

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha5	NP_477202.2	proteasome_alpha_type_5	8..222	CDD:239722	34/182 (19%)
PSMB3	NP_002786.2	proteasome_beta_type_3	6..201	CDD:239728	35/188 (19%)