Protein Alignment Prosalpha5 and PSMB1

DIOPT Version :10

• Sequence 1: NP_477202.2
• Gene: Prosalpha5 / 36951
• FlyBaseID: FBgn0016697
• Length: 244
• Species: Drosophila melanogaster
• Sequence 2: NP_002784.1
• Gene: PSMB1 / 5689
• HGNCID: 9537
• Length: 241
• Species: Homo sapiens
• Alignment Length: 237
• Identity: 58/237 - (24%)
• Similarity: 93/237 - (39%)
• Gaps: 72/237 - (30%)

  Fly    34 GSTAIGICTPEGVVLAVEKRIT---------SPLMVPSTVEKIVEVDKHIGCATSGLMADARTL- 88
            |.|.:.|...:..::|.:.|::         ||.....| :|.|     |||  ||...|..||
Human    37 GGTILAIAGEDFAIVASDTRLSEGFSIHTRDSPKCYKLT-DKTV-----IGC--SGFHGDCLTLT 93

  Fly    89 -IERARVECQNHWFVYNERMSIESCAQAVSTLAIQFGDSGDSDGAAAMSR---PFGVAILFAGI- 148
             |..||::...|  ..|:.|:..:.|..:||:              ..||   |:.|..:..|:
Human    94 KIIEARLKMYKH--SNNKAMTTGAIAAMLSTI--------------LYSRRFFPYYVYNIIGGLD 142

  Fly   149 EAGQPQLWHMDPSGTFVRHGAKAIGSGSEGAQ---------QNLQDLFRPDLTLDEAIDISLNTL 204
            |.|:..::..||.|::.|...||.||.|...|         :|:|::....|:||.|    :..:
Human   143 EEGKGAVYSFDPVGSYQRDSFKAGGSASAMLQPLLDNQVGFKNMQNVEHVPLSLDRA----MRLV 203

  Fly   205 KQVMEEKLNSTNVEVMTMTKEREFY--------MFTKEEVEQ 238
            |            :|.....||:.|        :.|||.:.:
Human   204 K------------DVFISAAERDVYTGDALRICIVTKEGIRE 233

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha5	NP_477202.2	proteasome_alpha_type_5	8..222	CDD:239722	52/211 (25%)
PSMB1	NP_002784.1	proteasome_beta_type_1	30..241	CDD:239726	58/237 (24%)