Protein Alignment Prosalpha5 and PSMA2

DIOPT Version :10

• Sequence 1: NP_477202.2
• Gene: Prosalpha5 / 36951
• FlyBaseID: FBgn0016697
• Length: 244
• Species: Drosophila melanogaster
• Sequence 2: NP_002778.1
• Gene: PSMA2 / 5683
• HGNCID: 9531
• Length: 234
• Species: Homo sapiens
• Alignment Length: 237
• Identity: 83/237 - (35%)
• Similarity: 126/237 - (53%)
• Gaps: 8/237 - (3%)

  Fly     8 YDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGICTPEGVVLAVEKRITSPLMVPSTVEKIVEVDK 72
            |...:.||||.|:|.|:|||:.|:..|:.::||....|||||.||:..|.|....:|.|:..:.|
Human     6 YSFSLTTFSPSGKLVQIEYALAAVAGGAPSVGIKAANGVVLATEKKQKSILYDERSVHKVEPITK 70

  Fly    73 HIGCATSGLMADARTLIERARVECQNHWFVYNERMSIESCAQAVSTLAIQFGDSGDSDGAAAMSR 137
            |||...||:..|.|.|:.|||...|.::.||.|.:......|.|:::..::..||.       .|
Human    71 HIGLVYSGMGPDYRVLVHRARKLAQQYYLVYQEPIPTAQLVQRVASVMQEYTQSGG-------VR 128

  Fly   138 PFGVAILFAGIEAGQPQLWHMDPSGTFVRHGAKAIGSGSEGAQQNLQDLFRPDLTLDEAIDISLN 202
            ||||::|..|...|:|.|:..||||.:....|.|:|......:..|:..:..||.|::||..::.
Human   129 PFGVSLLICGWNEGRPYLFQSDPSGAYFAWKATAMGKNYVNGKTFLEKRYNEDLELEDAIHTAIL 193

  Fly   203 TLKQVMEEKLNSTNVEVMTMTKEREFYMFTKEEVEQHIKNIA 244
            |||:..|.::...|:|| .:..|..|...|..||:.::..||
Human   194 TLKESFEGQMTEDNIEV-GICNEAGFRRLTPTEVKDYLAAIA 234

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha5	NP_477202.2	proteasome_alpha_type_5	8..222	CDD:239722	76/213 (36%)
PSMA2	NP_002778.1	proteasome_alpha_type_2	6..231	CDD:239719	81/232 (35%)