DRSC/TRiP Functional Genomics Resources

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Protein Alignment Prosalpha5 and PSMA1

DIOPT Version :9

Sequence 1:NP_477202.2 Gene:Prosalpha5 / 36951 FlyBaseID:FBgn0016697 Length:244 Species:Drosophila melanogaster
Sequence 2:NP_683877.1 Gene:PSMA1 / 5682 HGNCID:9530 Length:269 Species:Homo sapiens


Alignment Length:243 Identity:75/243 - (30%)
Similarity:123/243 - (50%) Gaps:13/243 - (5%)


- Green bases have known domain annotations that are detailed below.


  Fly     5 RSEYDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGICTPEGVVLAVEKRITSPLMVPSTVEKIVE 69
            |::||..|..:||:||:.|:|||:||:|.||..:|:.:....||...||..|.|....  :||:.
Human     9 RNQYDNDVTVWSPQGRIHQIEYAMEAVKQGSATVGLKSKTHAVLVALKRAQSELAAHQ--KKILH 71

  Fly    70 VDKHIGCATSGLMADARTLIERARVECQNHWFVYNERMSIESCAQAVSTLAIQFGDSGDSDGAAA 134
            ||.|||.:.:||.||||.|....|.||.:..||::..:       .||.|....|..........
Human    72 VDNHIGISIAGLTADARLLCNFMRQECLDSRFVFDRPL-------PVSRLVSLIGSKTQIPTQRY 129

  Fly   135 MSRPFGVAILFAGIEAGQPQLWHMDPSGTFVRHGAKAIGSGSEGAQQNLQDLFRP--DLTLDEAI 197
            ..||:||.:|.||.:...|.::...||..:....|.:||:.|:.|:..|:.....  :..|:|.:
Human   130 GRRPYGVGLLIAGYDDMGPHIFQTCPSANYFDCRAMSIGARSQSARTYLERHMSEFMECNLNELV 194

  Fly   198 DISLNTLKQVM--EEKLNSTNVEVMTMTKEREFYMFTKEEVEQHIKNI 243
            ...|..|::.:  |:.|.:.||.:..:.|:.||.::..::|...::.:
Human   195 KHGLRALRETLPAEQDLTTKNVSIGIVGKDLEFTIYDDDDVSPFLEGL 242

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Prosalpha5NP_477202.2 PRK03996 8..243 CDD:235192 74/238 (31%)
proteasome_alpha_type_5 8..222 CDD:239722 70/217 (32%)
PSMA1NP_683877.1 proteasome_alpha_type_1 12..222 CDD:239718 70/218 (32%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0638
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1222564at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.820

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