Protein Alignment Prosalpha5 and PSMA1

DIOPT Version :10

• Sequence 1: NP_477202.2
• Gene: Prosalpha5 / 36951
• FlyBaseID: FBgn0016697
• Length: 244
• Species: Drosophila melanogaster
• Sequence 2: NP_683877.1
• Gene: PSMA1 / 5682
• HGNCID: 9530
• Length: 269
• Species: Homo sapiens
• Alignment Length: 243
• Identity: 75/243 - (30%)
• Similarity: 123/243 - (50%)
• Gaps: 13/243 - (5%)

  Fly     5 RSEYDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGICTPEGVVLAVEKRITSPLMVPSTVEKIVE 69
            |::||..|..:||:||:.|:|||:||:|.||..:|:.:....||...||..|.|....  :||:.
Human     9 RNQYDNDVTVWSPQGRIHQIEYAMEAVKQGSATVGLKSKTHAVLVALKRAQSELAAHQ--KKILH 71

  Fly    70 VDKHIGCATSGLMADARTLIERARVECQNHWFVYNERMSIESCAQAVSTLAIQFGDSGDSDGAAA 134
            ||.|||.:.:||.||||.|....|.||.:..||::..:       .||.|....|..........
Human    72 VDNHIGISIAGLTADARLLCNFMRQECLDSRFVFDRPL-------PVSRLVSLIGSKTQIPTQRY 129

  Fly   135 MSRPFGVAILFAGIEAGQPQLWHMDPSGTFVRHGAKAIGSGSEGAQQNLQDLFRP--DLTLDEAI 197
            ..||:||.:|.||.:...|.::...||..:....|.:||:.|:.|:..|:.....  :..|:|.:
Human   130 GRRPYGVGLLIAGYDDMGPHIFQTCPSANYFDCRAMSIGARSQSARTYLERHMSEFMECNLNELV 194

  Fly   198 DISLNTLKQVM--EEKLNSTNVEVMTMTKEREFYMFTKEEVEQHIKNI 243
            ...|..|::.:  |:.|.:.||.:..:.|:.||.::..::|...::.:
Human   195 KHGLRALRETLPAEQDLTTKNVSIGIVGKDLEFTIYDDDDVSPFLEGL 242

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha5	NP_477202.2	proteasome_alpha_type_5	8..222	CDD:239722	70/217 (32%)
PSMA1	NP_683877.1	proteasome_alpha_type_1	12..222	CDD:239718	70/218 (32%)