DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Prosalpha5 and psma5

DIOPT Version :9

Sequence 1:	NP_477202.2	Gene:	Prosalpha5 / 36951	FlyBaseID:	FBgn0016697	Length:	244	Species:	Drosophila melanogaster
Sequence 2:	NP_991271.1	Gene:	psma5 / 403011	ZFINID:	ZDB-GENE-040625-96	Length:	241	Species:	Danio rerio

Alignment Length:	243	Identity:	170/243 - (69%)
Similarity:	203/243 - (83%)	Gaps:	2/243 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MFLTRSEYDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGICTPEGVVLAVEKRITSPLMVPSTVE 65
            ||||||||||||||||||||||||||||||||||||||||.|.|||.||||||||||||.||::|
Zfish     1 MFLTRSEYDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGIQTSEGVCLAVEKRITSPLMEPSSIE 65

  Fly    66 KIVEVDKHIGCATSGLMADARTLIERARVECQNHWFVYNERMSIESCAQAVSTLAIQFGDSGDSD 130
            ||||:|.|||||.|||:|||:|||::||||.|||||.|||.|::||..||||.||:|||:. |:|
Zfish    66 KIVEIDSHIGCAMSGLIADAKTLIDKARVETQNHWFTYNETMTVESVTQAVSNLALQFGEE-DAD 129

  Fly   131 GAAAMSRPFGVAILFAGIEAGQPQLWHMDPSGTFVRHGAKAIGSGSEGAQQNLQDLFRPDLTLDE 195
             ..|||||||||:||.|::...|||:|||||||||:..|:||||.|||||.:||:::...:||.:
Zfish   130 -PGAMSRPFGVALLFGGVDEKGPQLYHMDPSGTFVQCDARAIGSASEGAQSSLQEVYHKSMTLKD 193

  Fly   196 AIDISLNTLKQVMEEKLNSTNVEVMTMTKEREFYMFTKEEVEQHIKNI 243
            ||..||..||||||||||:||:|:.|:...:.|:|:||||:|..||:|
Zfish   194 AIKSSLTILKQVMEEKLNATNIELATVEPGKTFHMYTKEELEDVIKDI 241

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha5	NP_477202.2	PRK03996	8..243	CDD:235192	162/234 (69%)
Prosalpha5	NP_477202.2	proteasome_alpha_type_5	8..222	CDD:239722	152/213 (71%)
psma5	NP_991271.1	proteasome_alpha_type_5	8..220	CDD:239722	152/213 (71%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170576374
Domainoid	1	1.000	255	1.000	Domainoid score	I2012
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2084
Inparanoid	1	1.050	334	1.000	Inparanoid score	I2401
OMA	1	1.010	-	-		QHG54013
OrthoDB	1	1.010	-	-		D1222564at2759
OrthoFinder	1	1.000	-	-		FOG0004131
OrthoInspector	1	1.000	-	-		oto40879
orthoMCL	1	0.900	-	-		OOG6_101621
Panther	1	1.100	-	-	LDO	PTHR11599
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1007
SonicParanoid	1	1.000	-	-		X2875
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	17	16.800