DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosalpha5 and Prosbeta2

DIOPT Version :9

Sequence 1:	NP_477202.2	Gene:	Prosalpha5 / 36951	FlyBaseID:	FBgn0016697	Length:	244	Species:	Drosophila melanogaster
Sequence 2:	NP_524076.2	Gene:	Prosbeta2 / 39628	FlyBaseID:	FBgn0023174	Length:	272	Species:	Drosophila melanogaster

Alignment Length:	201	Identity:	39/201 - (19%)
Similarity:	85/201 - (42%)	Gaps:	14/201 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 KLGSTAIGICTPEGVVLAVEKRIT-SPLMVPSTVEKIVEVDKHIGCATSGLMADARTLIERARVE 95
            |.|:|.:||...:||:|..:.|.| .|::......||..:.|:|.|..:|..||.....:....:
  Fly    37 KTGTTIVGIIYKDGVILGADTRATEGPIVSDKNCAKIHYLAKNIYCCGAGTAADTEMTTDLISSQ 101

  Fly    96 CQNHWFVYNERMSIESCAQAVSTLAIQFGDSGDSDGAAAMSRPFGVAILFAGIEAGQPQLWHMDP 160
            .:.|....:..:.:.:....:..:..::            ......|::..|::...|.::.:.|
  Fly   102 LELHRLQTDREVRVVAANTMLKQMLFRY------------QGHISAALVLGGVDKTGPHIYSIHP 154

  Fly   161 SGTFVRHGAKAIGSGSEGAQQNLQDLFRPDLTLDEAIDISLNTLKQVMEEKLNS-TNVEVMTMTK 224
            .|:..:.....:||||..|....:..::|||:.:|...:..:.:...:...|.| :|:::..:.|
  Fly   155 HGSSDKLPYATMGSGSLAAMTVFESRWKPDLSEEEGKKLVRDAIASGVFNDLGSGSNIDLCVIRK 219

  Fly   225 EREFYM 230
            ....|:
  Fly   220 GSVEYL 225

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha5	NP_477202.2	PRK03996	8..243	CDD:235192	39/201 (19%)
Prosalpha5	NP_477202.2	proteasome_alpha_type_5	8..222	CDD:239722	37/191 (19%)
Prosbeta2	NP_524076.2	PRE1	42..232	CDD:223711	36/196 (18%)
		proteasome_beta_type_7	42..228	CDD:239732	36/196 (18%)
		Pr_beta_C	232..264	CDD:289249
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440995
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0638
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11599
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840