DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosalpha5 and Psmb10

DIOPT Version :9

Sequence 1:	NP_477202.2	Gene:	Prosalpha5 / 36951	FlyBaseID:	FBgn0016697	Length:	244	Species:	Drosophila melanogaster
Sequence 2:	NP_038668.2	Gene:	Psmb10 / 19171	MGIID:	1096380	Length:	273	Species:	Mus musculus

Alignment Length:	207	Identity:	50/207 - (24%)
Similarity:	91/207 - (43%)	Gaps:	36/207 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 AIKLGSTAIGICTPEGVVLAVEKRITSPLMV-PSTVEKIVEVDKHIGCATSGLMADARTLIERAR 93
            |.|.|:|..|:...:||:|..:.|.|:..:| ..:.|||..:...|.|..:|:.||.......|.
Mouse    35 ARKTGTTIAGLVFRDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCGAGVAADTEMTTRMAA 99

  Fly    94 VECQNHWFVYNERMSIESCAQAVSTLAIQFGDSGDSDGAAAMSR-----------PFGVAILFAG 147
            .:.:.|               |:||        |.....|.::|           ..|.:::..|
Mouse   100 SKMELH---------------ALST--------GREPRVATVTRILRQTLFRYQGHVGASLVVGG 141

  Fly   148 IEAGQPQLWHMDPSGTFVRHGAKAIGSGSEGAQQNLQDLFRPDLTLDEAIDISLNTLKQ-VMEEK 211
            ::...|||:.:.|.|::.|....|:|||...|...|:|.|:|::||:.|.::.:..:.. ::.:.
Mouse   142 VDLNGPQLYEVHPHGSYSRLPFTALGSGQGAAVALLEDRFQPNMTLEAAQELLVEAITAGILSDL 206

  Fly   212 LNSTNVEVMTMT 223
            .:..||:...:|
Mouse   207 GSGGNVDACVIT 218

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha5	NP_477202.2	PRK03996	8..243	CDD:235192	50/207 (24%)
Prosalpha5	NP_477202.2	proteasome_alpha_type_5	8..222	CDD:239722	49/204 (24%)
Psmb10	NP_038668.2	20S_bact_beta	39..238	CDD:163402	48/203 (24%)
		proteasome_beta_type_7	40..226	CDD:239732	47/202 (23%)
		Pr_beta_C	232..267	CDD:289249
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810