DRSC/TRiP Functional Genomics Resources

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Protein Alignment Prosalpha5 and PSMA8

DIOPT Version :9

Sequence 1:NP_477202.2 Gene:Prosalpha5 / 36951 FlyBaseID:FBgn0016697 Length:244 Species:Drosophila melanogaster
Sequence 2:NP_653263.2 Gene:PSMA8 / 143471 HGNCID:22985 Length:256 Species:Homo sapiens


Alignment Length:247 Identity:89/247 - (36%)
Similarity:136/247 - (55%) Gaps:18/247 - (7%)


- Green bases have known domain annotations that are detailed below.


  Fly     6 SEYDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGICTPEGVVLAVEKRITSPLMVPSTVEKIVEV 70
            |.|||.:..|||:|.|||||||.||:|.||||:||.....|||.|||:..:.|....||.||..:
Human     3 SRYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGIRGTNIVVLGVEKKSVAKLQDERTVRKICAL 67

  Fly    71 DKHIGCATS------GLMADARTLIERARVECQNHWFVYNERMSIESCAQAVSTLAIQFGDSGDS 129
            |.|:..|.:      ||.||||.:|.|||||||:|.....:.:::|...:.::||..::..|.. 
Human    68 DDHVCMAFAVLTIFIGLTADARVVINRARVECQSHKLTVEDPVTVEYITRFIATLKQKYTQSNG- 131

  Fly   130 DGAAAMSRPFGVAILFAGI-EAGQPQLWHMDPSGTFVRHGAKAIGSGSEGAQQNLQDLFRPDLTL 193
                  .||||::.|..|. :.|..:|:..|||||:....|.|||..::..::.|:..:..|...
Human   132 ------RRPFGISALIVGFDDDGISRLYQTDPSGTYHAWKANAIGRSAKTVREFLEKNYTEDAIA 190

  Fly   194 --DEAIDISLNTLKQVMEEKLNSTNVEVMTMTKEREFYMFTKEEVEQHIKNI 243
              .|||.:::..|.:|::.  ...|:|:..:.:.:...||:.:|||.::..|
Human   191 SDSEAIKLAIKALLEVVQS--GGKNIELAIIRRNQPLKMFSAKEVELYVTEI 240

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Prosalpha5NP_477202.2 PRK03996 8..243 CDD:235192 87/243 (36%)
proteasome_alpha_type_5 8..222 CDD:239722 82/222 (37%)
PSMA8NP_653263.2 PRK03996 5..237 CDD:235192 87/240 (36%)
proteasome_alpha_type_7 5..219 CDD:239724 82/222 (37%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0638
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1222564at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.820

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