Protein Alignment mbl and MBNL1

DIOPT Version :9

• Sequence 1: NP_001261046.1
• Gene: mbl / 36945
• FlyBaseID: FBgn0265487
• Length: 956
• Species: Drosophila melanogaster
• Sequence 2: NP_001363747.1
• Gene: MBNL1 / 4154
• HGNCID: 6923
• Length: 431
• Species: Homo sapiens
• Alignment Length: 462
• Identity: 172/462 - (37%)
• Similarity: 226/462 - (48%)
• Gaps: 111/462 - (24%)

  Fly    14 KDSRWLQLEVCREFQRNKCSRQDTECKFAHPPANVEVQNGKVTACYDSIK--------------- 63
            :|::||.|||||||||..|||.|||||||||..:.:|:||:|.||:||:|
Human     9 RDTKWLTLEVCREFQRGTCSRPDTECKFAHPSKSCQVENGRVIACFDSLKARATHFMENVTRSKV 73

  Fly    64 ----------------GRCNRDKPPCKYFHPPQHLKDQLLINGRNHL-ALKNALM--QQMGIA-- 107
                            |||:|:.  |||.|||.|||.||.|||||:| ..||..|  |||.:|
Human    74 LNCCYSTLPEAQTLLHGRCSREN--CKYLHPPPHLKTQLEINGRNNLIQQKNMAMLAQQMQLANA 136

  Fly   108 --PGQPVISGQVPAVATNPYL-TGIPANSYSPYY--TTGHLVPALL---GPDPVTSQLGPVVPQT 164
              ||.|:  ..||..:..|.| |...|.:::||.  .:..||||.:   .|..||...|..||..
Human   137 MMPGAPL--QPVPMFSVAPSLATNASAAAFNPYLGPVSPSLVPAEILPTAPMLVTGNPGVPVPAA 199

  Fly   165 VQVAQQKIPRSDRLEVCREFLRGACKRAESECRFAHPQES-VARHDDGSITVCMDAVKGRCARDP 228
            ...|.||:.|:||||||||:.||.|.|.|::||||||.:| :...:|.::|||||.:||||:|:.
Human   200 AAAAAQKLMRTDRLEVCREYQRGNCNRGENDCRFAHPADSTMIDTNDNTVTVCMDYIKGRCSREK 264

  Fly   229 CRYFHPPLHLQAQLKAAQ---TRATAVAAAAAVWLYTIYFSILFEPSLCMDVKTVGSFYYDNFQF 290
            |:|||||.||||::||||   .:|.|..|||.....|        .|....:|......:|....
Human   265 CKYFHPPAHLQAKIKAAQYQVNQAAAAQAAATAAAMT--------QSAVKSLKRPLEATFDLGIP 321

  Fly   291 SGMVP--FKRPAAEKS--GIPVYQPGATAYQQLMQPYVPVSCEYPQQQQQPPPQQQQQQQHQQQN 351
            ..::|  .||||.||:  ...|:..|...|||.:                   ...|.|||
Human   322 QAVLPPLPKRPALEKTNGATAVFNTGIFQYQQAL-------------------ANMQLQQH---- 363

  Fly   352 VLLQQQLQLSSVITTTSTTATASNNMINNNINNKGIINAVMASTNITSSATTTASSSLLSALGTP 416
               ...|...|::..|..|:               ::..|..:|..|.||.||:::|:      |
Human   364 ---TAFLPPGSILCMTPATS---------------VVPMVHGATPATVSAATTSATSV------P 404

  Fly   417 PTTTTTA 423
            ...|.||
Human   405 FAATATA 411

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mbl	NP_001261046.1	ZnF_C3H1	175..201	CDD:214632	17/25 (68%)
MBNL1	NP_001363747.1	ZnF_C3H1	212..236	CDD:214632	16/23 (70%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165147527
Domainoid	1	1.000	149	1.000	Domainoid score	I4462
eggNOG	1	0.900	-	-		E1_KOG2494
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	154	1.000	Inparanoid score	I4330
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001679
OrthoInspector	1	1.000	-	-		otm40923
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12675
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R11109
SonicParanoid	1	1.000	-	-		X1238
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	11	10.880